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Synthesis of Carvone Derivatives and In Silico and In Vitro Screening of Anti-Inflammatory Activity in Murine Macrophages

The chemical modification of natural compounds is a promising strategy to improve their frequently poor bioavailability and low potency. This study aimed at synthesizing chemical derivatives of carvone, a natural monoterpene with anti-inflammatory properties, which we recently identified, and evalua...

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Detalles Bibliográficos
Autores principales: Moço, Gabriela, Sousa, Cátia, Capitão, Ana, MacKinnon, Stephen Scott, Leitão, Alcino Jorge, Mendes, Alexandrina Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916994/
https://www.ncbi.nlm.nih.gov/pubmed/36768590
http://dx.doi.org/10.3390/ijms24032263