Cargando…
Synthesis of Carvone Derivatives and In Silico and In Vitro Screening of Anti-Inflammatory Activity in Murine Macrophages
The chemical modification of natural compounds is a promising strategy to improve their frequently poor bioavailability and low potency. This study aimed at synthesizing chemical derivatives of carvone, a natural monoterpene with anti-inflammatory properties, which we recently identified, and evalua...
Autores principales: | Moço, Gabriela, Sousa, Cátia, Capitão, Ana, MacKinnon, Stephen Scott, Leitão, Alcino Jorge, Mendes, Alexandrina Ferreira |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916994/ https://www.ncbi.nlm.nih.gov/pubmed/36768590 http://dx.doi.org/10.3390/ijms24032263 |
Ejemplares similares
-
Elucidation of the Mechanism Underlying the Anti-Inflammatory Properties of (S)-(+)-Carvone Identifies a Novel Class of Sirtuin-1 Activators in a Murine Macrophage Cell Line
por: Sousa, Cátia, et al.
Publicado: (2021) -
Molecular Mechanisms Underlying the Anti-Inflammatory Properties of (R)-(-)-Carvone: Potential Roles of JNK1, Nrf2 and NF-κB
por: Sousa, Cátia, et al.
Publicado: (2023) -
Standardised comparison of limonene-derived monoterpenes identifies structural determinants of anti-inflammatory activity
por: Sousa, Cátia, et al.
Publicado: (2020) -
Peer review of the pesticide risk assessment of the active substance carvone (substance evaluated d‐carvone)
por: Arena, Maria, et al.
Publicado: (2018) -
Bio-electrospraying assessment toward in situ chondrocyte-laden electrospun scaffold fabrication
por: Semitela, Ângela, et al.
Publicado: (2022)