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Inhibition of EZH2 Causes Retrotransposon Derepression and Immune Activation in Porcine Lung Alveolar Macrophages

Alveolar macrophages (AMs) form the first defense line against various respiratory pathogens, and their immune response has a profound impact on the outcome of respiratory infection. Enhancer of zeste homolog 2 (EZH2), which catalyzes the trimethylation of H3K27 for epigenetic repression, has gained...

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Detalles Bibliográficos
Autores principales: Zhang, Liangliang, Jin, Jian, Qin, Weiyun, Jiang, Jing, Bao, Wenbin, Sun, Ming-an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917017/
https://www.ncbi.nlm.nih.gov/pubmed/36768720
http://dx.doi.org/10.3390/ijms24032394