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Inhibition of EZH2 Causes Retrotransposon Derepression and Immune Activation in Porcine Lung Alveolar Macrophages
Alveolar macrophages (AMs) form the first defense line against various respiratory pathogens, and their immune response has a profound impact on the outcome of respiratory infection. Enhancer of zeste homolog 2 (EZH2), which catalyzes the trimethylation of H3K27 for epigenetic repression, has gained...
Autores principales: | Zhang, Liangliang, Jin, Jian, Qin, Weiyun, Jiang, Jing, Bao, Wenbin, Sun, Ming-an |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917017/ https://www.ncbi.nlm.nih.gov/pubmed/36768720 http://dx.doi.org/10.3390/ijms24032394 |
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