IRAK2 Downregulation in Triple-Negative Breast Cancer Cells Decreases Cellular Growth In Vitro and Delays Tumour Progression in Murine Models

Breast cancer stem cells (BCSCs) are responsible for tumour recurrence and therapy resistance. We have established primary BCSC cultures from human tumours of triple-negative breast cancer (TNBC), a subgroup of breast cancer likely driven by BCSCs. Primary BCSCs produce xenografts that phenocopy the...

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Detalles Bibliográficos
Autores principales: Ferraro, Francesca, Steinle, Anja, Narasimhan, Harini, Bleilevens, Andreas, Stolzenberg, Paula-Marie, Braunschweig, Till, Stickeler, Elmar, Maurer, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917074/
https://www.ncbi.nlm.nih.gov/pubmed/36768848
http://dx.doi.org/10.3390/ijms24032520

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