The ATR Inhibitor VE-821 Enhances the Radiosensitivity and Suppresses DNA Repair Mechanisms of Human Chondrosarcoma Cells

To overcome the resistance to radiotherapy in chondrosarcomas, the prevention of efficient DNA repair with an additional treatment was explored for particle beams as well as reference X-ray irradiation. The combined treatment with DNA repair inhibitors—with a focus on ATRi VE-821—and proton or carbo...

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Detalles Bibliográficos
Autores principales: Lohberger, Birgit, Glänzer, Dietmar, Eck, Nicole, Stasny, Katharina, Falkner, Anna, Leithner, Andreas, Georg, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917087/
https://www.ncbi.nlm.nih.gov/pubmed/36768638
http://dx.doi.org/10.3390/ijms24032315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917087/
https://www.ncbi.nlm.nih.gov/pubmed/36768638
http://dx.doi.org/10.3390/ijms24032315

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