Voriconazole Eye Drops: Enhanced Solubility and Stability through Ternary Voriconazole/Sulfobutyl Ether β-Cyclodextrin/Polyvinyl Alcohol Complexes

Voriconazole (VCZ) is a broad-spectrum antifungal agent used to treat ocular fungal keratitis. However, VCZ has low aqueous solubility and chemical instability in aqueous solutions. This study aimed to develop VCZ eye drop formulations using cyclodextrin (CD) and water-soluble polymers, forming CD c...

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Detalles Bibliográficos
Autores principales: Soe, Hay Man Saung Hnin, Kerdpol, Khanittha, Rungrotmongkol, Thanyada, Pruksakorn, Patamaporn, Autthateinchai, Rinrapas, Wet-osot, Sirawit, Loftsson, Thorsteinn, Jansook, Phatsawee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917179/
https://www.ncbi.nlm.nih.gov/pubmed/36768671
http://dx.doi.org/10.3390/ijms24032343

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