Cargando…

Zinc Inhibits the GABA(A)R/ATPase during Postnatal Rat Development: The Role of Cysteine Residue

Zinc ions (Zn(2+)) are concentrated in various brain regions and can act as a neuromodulator, targeting a wide spectrum of postsynaptic receptors and enzymes. Zn(2+) inhibits the GABA(A)Rs, and its potency is profoundly affected by the subunit composition and neuronal developmental stage. Although t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Menzikov, Sergey A., Zaichenko, Danila M., Moskovtsev, Aleksey A., Morozov, Sergey G., Kubatiev, Aslan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917249/ https://www.ncbi.nlm.nih.gov/pubmed/36769085 http://dx.doi.org/10.3390/ijms24032764

Ejemplares similares

Physiological Role of ATPase for GABA(A) Receptor Resensitization
por: Menzikov, Sergey A., et al.
Publicado: (2022)

Intricacies of GABA(A) Receptor Function: The Critical Role of the β3 Subunit in Norm and Pathology
por: Menzikov, Sergey A., et al.
Publicado: (2021)

Changes in the Surface Expression of Intercellular Adhesion Molecule 3, the Induction of Apoptosis, and the Inhibition of Cell-Cycle Progression of Human Multidrug-Resistant Jurkat/A4 Cells Exposed to a Random Positioning Machine
por: Sokolovskaya, Alisa, et al.
Publicado: (2020)

Differential processing of small RNAs during endoplasmic reticulum stress
por: Mesitov, Mikhail V., et al.
Publicado: (2017)

Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na(+),K(+)-ATPase-mediated signaling
por: Smolyaninova, Larisa V., et al.
Publicado: (2019)

Potential of Stem Cells and CART as a Potential Polytherapy for Small Cell Lung Cancer
por: Skurikhin, Evgenii, et al.
Publicado: (2021)

GABA operates upstream of H(+)-ATPase and improves salinity tolerance in Arabidopsis by enabling cytosolic K(+) retention and Na(+) exclusion
por: Su, Nana, et al.
Publicado: (2019)

Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding
por: Pérez-Sala, Dolores, et al.
Publicado: (2015)

Cysteine residues 244 and 458–459 within the catalytic subunit of Na,K-ATPase control the enzyme's hydrolytic and signaling function under hypoxic conditions
por: Petrushanko, Irina Yu., et al.
Publicado: (2017)

Multiple Tyrosine Residues Contribute to GABA Binding in the GABA(C) Receptor Binding Pocket
por: Lummis, Sarah C. R., et al.
Publicado: (2011)

Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition
por: Barykin, Evgeny P., et al.
Publicado: (2018)

Cancer Stem Cells and Somatic Stem Cells as Potential New Drug Targets, Prognosis Markers, and Therapy Efficacy Predictors in Breast Cancer Treatment
por: Pershina, Olga, et al.
Publicado: (2021)

Identifying Redox-Sensitive Cysteine Residues in Mitochondria
por: Kisty, Eleni A., et al.
Publicado: (2023)

Redox-sensitive DNA binding by homodimeric Methanosarcina acetivorans MsvR is modulated by cysteine residues
por: Isom, Catherine E, et al.
Publicado: (2013)

Spiperone Stimulates Regeneration in Pulmonary Endothelium Damaged by Cigarette Smoke and Lipopolysaccharide
por: Skurikhin, Evgenii, et al.
Publicado: (2021)

Characterization of redox-active cysteine residues of persulfide-responsive transcriptional repressor SqrR
por: Shimizu, Takayuki, et al.
Publicado: (2017)

The role of conserved residues of chagasin in the inhibition of cysteine peptidases
por: dos Reis, Flavia C.G., et al.
Publicado: (2008)

Context‐Dependence of the Reactivity of Cysteine and Lysine Residues
por: Boll, Linus B., et al.
Publicado: (2022)

Antifibrotic and Regenerative Effects of Treamid in Pulmonary Fibrosis
por: Skurikhin, Evgenii, et al.
Publicado: (2020)

Reprogrammed CD8(+) T-Lymphocytes Isolated from Bone Marrow Have Anticancer Potential in Lung Cancer
por: Skurikhin, Evgenii G., et al.
Publicado: (2022)

Cell Therapy with Human Reprogrammed CD8(+) T-Cells Has Antimetastatic Effects on Lewis Lung Carcinoma in C57BL/6 Mice
por: Skurikhin, Evgenii G., et al.
Publicado: (2022)

Molecular Insight into the Regulation of Vimentin by Cysteine Modifications and Zinc Binding
por: Mónico, Andreia, et al.
Publicado: (2021)

Functional role of ambient GABA in refining neuronal circuits early in postnatal development
por: Cellot, Giada, et al.
Publicado: (2013)

Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior
por: Li, Suyan, et al.
Publicado: (2018)

Chromatin and extracellular vesicle associated sperm RNAs
por: Johnson, Graham D., et al.
Publicado: (2015)

Perinatal Pb(2+) exposure alters the expression of genes related to the neurodevelopmental GABA-shift in postnatal rats
por: Neuwirth, Lorenz S., et al.
Publicado: (2018)

Accessibility of Myofilament Cysteines and Effects on ATPase Depend on the Activation State during Exposure to Oxidants
por: Gross, Sean M., et al.
Publicado: (2013)

Zinc-Binding Cysteines: Diverse Functions and Structural Motifs
por: Pace, Nicholas J., et al.
Publicado: (2014)

The level and distribution of the GABA(B)R1 and GABA(B)R2 receptor subunits in the rat's inferior colliculus
por: Jamal, Lena, et al.
Publicado: (2012)

GABA(B) Receptor-Mediated Impairment of Intermediate Progenitor Maturation During Postnatal Hippocampal Neurogenesis of Newborn Rats
por: Gustorff, Charlotte, et al.
Publicado: (2021)

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics
por: Mónico, Andreia, et al.
Publicado: (2019)

The expression and localization of V-ATPase and cytokeratin 5 during postnatal development of the pig epididymis
por: Park, Yun-Jae, et al.
Publicado: (2020)

Hippocampal Gene Expression of Deiodinases 2 and 3 and Effects of 3,5-Diiodo-L-Thyronine T2 in Mouse Depression Paradigms
por: Markova, Natalyia, et al.
Publicado: (2013)

Assessing spermatozoal small ribonucleic acids and their relationship to blastocyst development in idiopathic infertile males
por: Hamilton, Matthew, et al.
Publicado: (2022)

Role of the Rhamnosyl Residue of Ouabain in the Activation of the Na,K-ATPase Signaling Function
por: Rogachevskii, Ilya V., et al.
Publicado: (2023)

GABA(B)R silencing of nerve terminals
por: Cook, Daniel C, et al.
Publicado: (2023)

Increased Cell Fusion in Cerebral Cortex May Contribute to Poststroke Regeneration
por: Paltsyn, Alexander, et al.
Publicado: (2013)

Analysis of Circulating Tumor and Cancer Stem Cells Provides New Opportunities in Diagnosis and Treatment of Small Cell Lung Cancer
por: Skurikhin, Evgenii G., et al.
Publicado: (2022)

During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons
por: Brown, Adam R., et al.
Publicado: (2016)

Inactivation of human DGAT2 by oxidative stress on cysteine residues
por: Jung, Sunhee, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kpked81182kbnkbplsdfo0k680