Phillygenin Attenuated Colon Inflammation and Improved Intestinal Mucosal Barrier in DSS-induced Colitis Mice via TLR4/Src Mediated MAPK and NF-κB Signaling Pathways

Ulcerative colitis (UC) is a chronic, relapsing, and nonspecific inflammatory bowel disease (IBD). Phillygenin (PHI), a natural bioactive ingredient, isolated from Forsythiae Fructus, exhibits anti-inflammatory, anti-oxidative, and hepatoprotective activities. However, few reports provide direct evi...

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Detalles Bibliográficos
Autores principales: Xue, Huan-Huan, Li, Jing-Jing, Li, Shi-Fei, Guo, Jing, Yan, Rui-Ping, Chen, Ting-Gui, Shi, Xiang-Hua, Wang, Jin-Dong, Zhang, Li-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917337/
https://www.ncbi.nlm.nih.gov/pubmed/36768559
http://dx.doi.org/10.3390/ijms24032238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917337/
https://www.ncbi.nlm.nih.gov/pubmed/36768559
http://dx.doi.org/10.3390/ijms24032238

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