A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations

Dry eye disease is among the most prevalent diseases affecting the ocular surface. Artificial tears remain the cornerstone therapy for its management. There are currently a wide variety of marketed artificial tears available to choose from. These artificial tears differ significantly in their compos...

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Detalles Bibliográficos
Autores principales: Weng, Judy, Fink, Michael K., Sharma, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917348/
https://www.ncbi.nlm.nih.gov/pubmed/36769079
http://dx.doi.org/10.3390/ijms24032758
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author Weng, Judy
Fink, Michael K.
Sharma, Ajay
author_facet Weng, Judy
Fink, Michael K.
Sharma, Ajay
author_sort Weng, Judy
collection PubMed
description Dry eye disease is among the most prevalent diseases affecting the ocular surface. Artificial tears remain the cornerstone therapy for its management. There are currently a wide variety of marketed artificial tears available to choose from. These artificial tears differ significantly in their composition and formulation. This article reviews the physicochemical and biological properties of artificial tear components and how these characteristics determine their use and efficacy in the management of dry eye. Furthermore, this article also discusses the various formulations of artificial tears such as macro and nanoemulsion and the type of preservatives present in them.
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spelling pubmed-99173482023-02-11 A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations Weng, Judy Fink, Michael K. Sharma, Ajay Int J Mol Sci Review Dry eye disease is among the most prevalent diseases affecting the ocular surface. Artificial tears remain the cornerstone therapy for its management. There are currently a wide variety of marketed artificial tears available to choose from. These artificial tears differ significantly in their composition and formulation. This article reviews the physicochemical and biological properties of artificial tear components and how these characteristics determine their use and efficacy in the management of dry eye. Furthermore, this article also discusses the various formulations of artificial tears such as macro and nanoemulsion and the type of preservatives present in them. MDPI 2023-02-01 /pmc/articles/PMC9917348/ /pubmed/36769079 http://dx.doi.org/10.3390/ijms24032758 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Weng, Judy
Fink, Michael K.
Sharma, Ajay
A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations
title A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations
title_full A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations
title_fullStr A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations
title_full_unstemmed A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations
title_short A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations
title_sort critical appraisal of the physicochemical properties and biological effects of artificial tear ingredients and formulations
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917348/
https://www.ncbi.nlm.nih.gov/pubmed/36769079
http://dx.doi.org/10.3390/ijms24032758
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