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N6-methyladenosine Modification of Hepatitis B Virus RNA in the Coding Region of HBx
N6-methyladenosine (m(6)A) is a post-transcriptional modification of RNA involved in transcript transport, degradation, translation, and splicing. We found that HBV RNA is modified by m(6)A predominantly in the coding region of HBx. The mutagenesis of methylation sites reduced the HBV mRNA and HBs p...
Autores principales: | Murata, Takayuki, Iwahori, Satoko, Okuno, Yusuke, Nishitsuji, Hironori, Yanagi, Yusuke, Watashi, Koichi, Wakita, Takaji, Kimura, Hiroshi, Shimotohno, Kunitada |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917364/ https://www.ncbi.nlm.nih.gov/pubmed/36768585 http://dx.doi.org/10.3390/ijms24032265 |
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