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Supt16 Haploinsufficiency Impairs PI3K/AKT/mTOR/Autophagy Pathway in Human Pluripotent Stem Cells Derived Neural Stem Cells

The maintenance of neural stem cells (NSCs) plays a critical role in neurodevelopment and has been implicated in neurodevelopmental disorders (NDDs). However, the underlying mechanisms linking defective human neural stem cell self-renewal to NDDs remain undetermined. Our previous study found that Su...

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Detalles Bibliográficos
Autores principales:	Wang, Junwen, Wang, Ziyi, Dai, Limeng, Zhu, Xintong, Guan, Xingying, Wang, Junyi, Li, Jia, Zhang, Mao, Bai, Yun, Guo, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917370/ https://www.ncbi.nlm.nih.gov/pubmed/36769360 http://dx.doi.org/10.3390/ijms24033035

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