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Synthesis, Biological and In Silico Studies of Griseofulvin and Usnic Acid Sulfonamide Derivatives as Fungal, Bacterial and Human Carbonic Anhydrase Inhibitors

Carbonic anhydrases (CAs, EC 4.2.1.1) catalyze the essential reaction of CO(2) hydration in all living organisms, being actively involved in the regulation of a plethora of patho-/physiological conditions. A series of griseofulvin and usnic acid sulfonamides were synthesized and tested as possible C...

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Detalles Bibliográficos
Autores principales: Angeli, Andrea, Petrou, Anthi, Kartsev, Victor, Lichitsky, Boris, Komogortsev, Andrey, Capasso, Clemente, Geronikaki, Athina, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917406/
https://www.ncbi.nlm.nih.gov/pubmed/36769114
http://dx.doi.org/10.3390/ijms24032802