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Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy

The aim of this study was to investigate the effects of atropine on patients’ perception of visual quality after trabeculectomy. Forty patients undergoing standard trabeculectomy with mitomycin C were enrolled in this prospective randomized study. All surgeries were conducted at the ophthalmology de...

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Autores principales: Laspas, Panagiotis, Maier, Elisa, Schuster, Alexander, McAlinden, Colm, Pfeiffer, Norbert, Hoffmann, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917408/
https://www.ncbi.nlm.nih.gov/pubmed/36769412
http://dx.doi.org/10.3390/jcm12030763
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author Laspas, Panagiotis
Maier, Elisa
Schuster, Alexander
McAlinden, Colm
Pfeiffer, Norbert
Hoffmann, Esther
author_facet Laspas, Panagiotis
Maier, Elisa
Schuster, Alexander
McAlinden, Colm
Pfeiffer, Norbert
Hoffmann, Esther
author_sort Laspas, Panagiotis
collection PubMed
description The aim of this study was to investigate the effects of atropine on patients’ perception of visual quality after trabeculectomy. Forty patients undergoing standard trabeculectomy with mitomycin C were enrolled in this prospective randomized study. All surgeries were conducted at the ophthalmology department of the University Medical Center of Mainz, Germany. All patients received the same postoperative treatment with ofloxacin and dexamethasone eye drops. Following randomization of patients into two groups of 20 patients, the intervention group also received atropine eye drops three times daily for the first 2 days after surgery to stabilize the anterior chamber. All patients completed a visual quality questionnaire before surgery and 2 and 6 weeks after surgery. Results were compared using the Wilcoxon test. After surgery, there was a reduction in visual quality in all patients. Patients who received atropine eye drops described a greater and longer-lasting reduction in visual quality than those who did not receive atropine eye drops. Trabeculectomy often leads to a transient reduction in visual quality. This reduction was greater in severity and duration in patients who received postoperative atropine eye drops. Thus, unless there is an underlying medical necessity, we would discourage the application of atropine as a standard therapy for trabeculectomy surgery.
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spelling pubmed-99174082023-02-11 Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy Laspas, Panagiotis Maier, Elisa Schuster, Alexander McAlinden, Colm Pfeiffer, Norbert Hoffmann, Esther J Clin Med Brief Report The aim of this study was to investigate the effects of atropine on patients’ perception of visual quality after trabeculectomy. Forty patients undergoing standard trabeculectomy with mitomycin C were enrolled in this prospective randomized study. All surgeries were conducted at the ophthalmology department of the University Medical Center of Mainz, Germany. All patients received the same postoperative treatment with ofloxacin and dexamethasone eye drops. Following randomization of patients into two groups of 20 patients, the intervention group also received atropine eye drops three times daily for the first 2 days after surgery to stabilize the anterior chamber. All patients completed a visual quality questionnaire before surgery and 2 and 6 weeks after surgery. Results were compared using the Wilcoxon test. After surgery, there was a reduction in visual quality in all patients. Patients who received atropine eye drops described a greater and longer-lasting reduction in visual quality than those who did not receive atropine eye drops. Trabeculectomy often leads to a transient reduction in visual quality. This reduction was greater in severity and duration in patients who received postoperative atropine eye drops. Thus, unless there is an underlying medical necessity, we would discourage the application of atropine as a standard therapy for trabeculectomy surgery. MDPI 2023-01-18 /pmc/articles/PMC9917408/ /pubmed/36769412 http://dx.doi.org/10.3390/jcm12030763 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Laspas, Panagiotis
Maier, Elisa
Schuster, Alexander
McAlinden, Colm
Pfeiffer, Norbert
Hoffmann, Esther
Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy
title Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy
title_full Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy
title_fullStr Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy
title_full_unstemmed Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy
title_short Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy
title_sort effects of postoperative atropine eye drops on visual quality in patients undergoing trabeculectomy
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917408/
https://www.ncbi.nlm.nih.gov/pubmed/36769412
http://dx.doi.org/10.3390/jcm12030763
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