Soluble amyloid-β precursor peptide does not regulate GABA(B) receptor activity

Amyloid-β precursor protein (APP) regulates neuronal activity through the release of secreted APP (sAPP) acting at cell surface receptors. APP and sAPP were reported to bind to the extracellular sushi domain 1 (SD1) of GABA(B) receptors (GBRs). A 17 amino acid peptide (APP17) derived from APP was su...

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Detalles Bibliográficos
Autores principales: Rem, Pascal Dominic, Sereikaite, Vita, Fernández-Fernández, Diego, Reinartz, Sebastian, Ulrich, Daniel, Fritzius, Thorsten, Trovo, Luca, Roux, Salomé, Chen, Ziyang, Rondard, Philippe, Pin, Jean-Philippe, Schwenk, Jochen, Fakler, Bernd, Gassmann, Martin, Barkat, Tania Rinaldi, Strømgaard, Kristian, Bettler, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917443/
https://www.ncbi.nlm.nih.gov/pubmed/36688536
http://dx.doi.org/10.7554/eLife.82082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917443/
https://www.ncbi.nlm.nih.gov/pubmed/36688536
http://dx.doi.org/10.7554/eLife.82082

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