Cargando…

Insights into the Peritumoural Brain Zone of Glioblastoma: CDK4 and EXT2 May Be Potential Drivers of Malignancy

Despite the efforts made in recent decades, glioblastoma is still the deadliest primary brain cancer without cure. The potential role in tumour maintenance and progression of the peritumoural brain zone (PBZ), the apparently normal area surrounding the tumour, has emerged. Little is known about this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giambra, Martina, Di Cristofori, Andrea, Conconi, Donatella, Marzorati, Matilde, Redaelli, Serena, Zambuto, Melissa, Rocca, Alessandra, Roumy, Louis, Carrabba, Giorgio, Lavitrano, Marialuisa, Roversi, Gaia, Giussani, Carlo, Bentivegna, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917451/ https://www.ncbi.nlm.nih.gov/pubmed/36769158 http://dx.doi.org/10.3390/ijms24032835

Ejemplares similares

Characterizing the Genomic Profile in High-Grade Gliomas: From Tumor Core to Peritumoral Brain Zone, Passing through Glioma-Derived Tumorspheres
por: Giambra, Martina, et al.
Publicado: (2021)

Analysis of copy number alterations in bladder cancer stem cells revealed a prognostic role of LRP1B
por: Conconi, Donatella, et al.
Publicado: (2022)

Characterization of Chromosomal Breakpoints in 12 Cases with 8p Rearrangements Defines a Continuum of Fragility of the Region
por: Redaelli, Serena, et al.
Publicado: (2022)

AhRR and PPP1R3C: Potential Prognostic Biomarkers for Serous Ovarian Cancer
por: Ardizzoia, Alessandra, et al.
Publicado: (2023)

Genomic Complexity and Complex Chromosomal Rearrangements in Genetic Diagnosis: Two Illustrative Cases on Chromosome 7
por: Villa, Nicoletta, et al.
Publicado: (2023)

Genomic and Epigenomic Profile of Uterine Smooth Muscle Tumors of Uncertain Malignant Potential (STUMPs) Revealed Similarities and Differences with Leiomyomas and Leiomyosarcomas
por: Conconi, Donatella, et al.
Publicado: (2021)

Familiar unbalanced complex rearrangements involving 13 p-arm: description of two cases
por: Conconi, Donatella, et al.
Publicado: (2018)

Human Chromosome 18 and Acrocentrics: A Dangerous Liaison
por: Villa, Nicoletta, et al.
Publicado: (2021)

Using Copy Number Alterations to Identify New Therapeutic Targets for Bladder Carcinoma
por: Conconi, Donatella, et al.
Publicado: (2016)

Instability of Short Arm of Acrocentric Chromosomes: Lesson from Non-Acrocentric Satellited Chromosomes. Report of 24 Unrelated Cases
por: Redaelli, Serena, et al.
Publicado: (2020)

Patient-Derived Induced Pluripotent Stem Cells (iPSCs) and Cerebral Organoids for Drug Screening and Development in Autism Spectrum Disorder: Opportunities and Challenges
por: Villa, Chiara, et al.
Publicado: (2021)

Peritumoural Strain Elastography of Newly Diagnosed Breast Tumours: Does Maximum Peritumoural Halo Depth Correlate with Tumour Differentiation and Grade?
por: Gruber, Leonhard, et al.
Publicado: (2023)

Refining the Phenotype of Recurrent Rearrangements of Chromosome 16
por: Redaelli, Serena, et al.
Publicado: (2019)

The peritumoral brain zone in glioblastoma: where we are and where we are going
por: Giambra, Martina, et al.
Publicado: (2022)

Exoscope and operative microscope for training in microneurosurgery: A laboratory investigation on a model of cranial approach
por: Calloni, Tommaso, et al.
Publicado: (2023)

Potential role of BCL2 in the recurrence of uterine smooth muscle tumors of uncertain malignant potential
por: Conconi, Donatella, et al.
Publicado: (2017)

p65BTK Is a Novel Biomarker and Therapeutic Target in Solid Tumors
por: Grassilli, Emanuela, et al.
Publicado: (2021)

19q12q13.2 duplication syndrome: neuropsychiatric long-term follow-up of a new case and literature update
por: Nacinovich, Renata, et al.
Publicado: (2017)

Fluorescence and Intraoperative Ultrasound as Surgical Adjuncts for Brain Metastases Resection: What Do We Know? A Systematic Review of the Literature
por: Di Cristofori, Andrea, et al.
Publicado: (2023)

Exoscope as a Teaching Tool: A Narrative Review of the Literature
por: Calloni, Tommaso, et al.
Publicado: (2022)

MINOS: Bt 376 - 599 ext - 376 ext - AP (100)
Publicado: (1991)

Unexpected frequency of genomic alterations in histologically normal colonic tissue from colon cancer patients
por: Conconi, Donatella, et al.
Publicado: (2016)

Mastering Ext JS
por: Groner, Loiane
Publicado: (2015)

Learning Ext JS
por: Méndez, Carlos A, et al.
Publicado: (2015)

Ext JS in action
por: García, Jesús
Publicado: (2011)

Learning Ext JS
por: Ramsay, Colin, et al.
Publicado: (2008)

Ext JS in action
por: Garcia, Jesus, et al.
Publicado: (2014)

Mutations in the EXT1 and EXT2 genes in Spanish patients with multiple osteochondromas
por: Sarrión, P., et al.
Publicado: (2013)

Analysis of mutations in EXT1 and EXT2 in Brazilian patients with multiple osteochondromas
por: Santos, Savana C. L., et al.
Publicado: (2018)

Structure of the human heparan sulfate polymerase complex EXT1-EXT2
por: Leisico, Francisco, et al.
Publicado: (2022)

Mutation spectrum of EXT1 and EXT2 in the Saudi patients with hereditary multiple exostoses
por: Al-Zayed, Zayed, et al.
Publicado: (2021)

Evaluating [(18)F]FDG and [(18)F]FLT Radiotracers as Biomarkers of Response for Combined Therapy Outcome in Triple-Negative and Estrogen-Receptor-Positive Breast Cancer Models
por: Rainone, Paolo, et al.
Publicado: (2023)

Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin
por: Omland, Silje Haukali, et al.
Publicado: (2017)

Practical Ext JS 4
por: Sunderaraman, Prabhu
Publicado: (2013)

Learning Ext JS 4
por: Villa, Crysfel, et al.
Publicado: (2013)

Breakpoint characterization of large deletions in EXT1 or EXT2 in 10 Multiple Osteochondromas families
por: Jennes, Ivy, et al.
Publicado: (2011)

Mutational screening of EXT1 and EXT2 genes in Polish patients with hereditary multiple exostoses
por: Jamsheer, Aleksander, et al.
Publicado: (2014)

A broad spectrum of genomic changes in latinamerican patients with EXT1/EXT2-CDG
por: Delgado, M. A., et al.
Publicado: (2014)

Chromosomal imbalances in human bladder urothelial carcinoma: similarities and differences between biopsy samples and cancer stem-like cells
por: Conconi, Donatella, et al.
Publicado: (2014)

Correction to: Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin
por: Omland, Silje Haukali, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cgkg14r2ggno9edp6cvehs8u9d