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The Autotaxin-LPA Axis Emerges as a Novel Regulator of Smooth Muscle Cell Phenotypic Modulation during Intimal Hyperplasia

Neointimal hyperplasia is characterized by a loss of the contractile phenotype of vascular smooth muscle cells (VSMCs). Our group has recently shown that VSMC proliferation and migration are mediated by lysophosphatidic acid (LPA) during restenosis, but the role of autotaxin (ATX; lysophospholipase...

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Detalles Bibliográficos
Autores principales: Subedi, Utsab, Manikandan, Shrivats, Bhattarai, Susmita, Sharma, Papori, Sharma, Sudha, Sun, Hong, Miriyala, Sumitra, Panchatcharam, Manikandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917461/
https://www.ncbi.nlm.nih.gov/pubmed/36769255
http://dx.doi.org/10.3390/ijms24032913