Cargando…
Modified Carnoy’s Versus Carnoy’s Solution in the Management of Odontogenic Keratocysts—A Single Center Experience
To date, few studies have been conducted to test the effectiveness of Carnoy’s (CS) versus modified Carnoy’s (MC) solution for preventing the recurrence of odontogenic keratocysts, which are potentially aggressive lesions. To evaluate the efficacy of MC application, we conducted a retrospective coho...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917467/ https://www.ncbi.nlm.nih.gov/pubmed/36769783 http://dx.doi.org/10.3390/jcm12031133 |
_version_ | 1784886373464932352 |
---|---|
author | Janas-Naze, Anna Zhang, Wei Szuta, Mariusz |
author_facet | Janas-Naze, Anna Zhang, Wei Szuta, Mariusz |
author_sort | Janas-Naze, Anna |
collection | PubMed |
description | To date, few studies have been conducted to test the effectiveness of Carnoy’s (CS) versus modified Carnoy’s (MC) solution for preventing the recurrence of odontogenic keratocysts, which are potentially aggressive lesions. To evaluate the efficacy of MC application, we conducted a retrospective cohort study over an 18-year period, from October 2004 to October 2022, in 122 patients treated surgically with adjunctive chemical cautery, with either CS (n = 73; median age: 30 years) or MC (n = 49; median age: 42 years), by a single surgeon. The primary outcome variables were observed recurrence and interval to recurrence. Independent variables were demographics, location, clinical presentation at baseline, adjacent tooth extraction, and bone grafting. Males predominated in both groups. No statistically significant differences were observed between the two arms in terms of recurrences in particular months, with six patients (8.2%) in the CS arm and 5 (10.2%) in the MC arm. Of the 11 recurrences, 10 were observed within the first 2 years post-surgery, with only one occurring in the 7th year of follow-up. Thus, when used as adjunctive therapy, the application of MC has an efficiency comparable to that of CS for lowering the recurrence rate of odontogenic keratocysts. |
format | Online Article Text |
id | pubmed-9917467 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99174672023-02-11 Modified Carnoy’s Versus Carnoy’s Solution in the Management of Odontogenic Keratocysts—A Single Center Experience Janas-Naze, Anna Zhang, Wei Szuta, Mariusz J Clin Med Article To date, few studies have been conducted to test the effectiveness of Carnoy’s (CS) versus modified Carnoy’s (MC) solution for preventing the recurrence of odontogenic keratocysts, which are potentially aggressive lesions. To evaluate the efficacy of MC application, we conducted a retrospective cohort study over an 18-year period, from October 2004 to October 2022, in 122 patients treated surgically with adjunctive chemical cautery, with either CS (n = 73; median age: 30 years) or MC (n = 49; median age: 42 years), by a single surgeon. The primary outcome variables were observed recurrence and interval to recurrence. Independent variables were demographics, location, clinical presentation at baseline, adjacent tooth extraction, and bone grafting. Males predominated in both groups. No statistically significant differences were observed between the two arms in terms of recurrences in particular months, with six patients (8.2%) in the CS arm and 5 (10.2%) in the MC arm. Of the 11 recurrences, 10 were observed within the first 2 years post-surgery, with only one occurring in the 7th year of follow-up. Thus, when used as adjunctive therapy, the application of MC has an efficiency comparable to that of CS for lowering the recurrence rate of odontogenic keratocysts. MDPI 2023-02-01 /pmc/articles/PMC9917467/ /pubmed/36769783 http://dx.doi.org/10.3390/jcm12031133 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Janas-Naze, Anna Zhang, Wei Szuta, Mariusz Modified Carnoy’s Versus Carnoy’s Solution in the Management of Odontogenic Keratocysts—A Single Center Experience |
title | Modified Carnoy’s Versus Carnoy’s Solution in the Management of Odontogenic Keratocysts—A Single Center Experience |
title_full | Modified Carnoy’s Versus Carnoy’s Solution in the Management of Odontogenic Keratocysts—A Single Center Experience |
title_fullStr | Modified Carnoy’s Versus Carnoy’s Solution in the Management of Odontogenic Keratocysts—A Single Center Experience |
title_full_unstemmed | Modified Carnoy’s Versus Carnoy’s Solution in the Management of Odontogenic Keratocysts—A Single Center Experience |
title_short | Modified Carnoy’s Versus Carnoy’s Solution in the Management of Odontogenic Keratocysts—A Single Center Experience |
title_sort | modified carnoy’s versus carnoy’s solution in the management of odontogenic keratocysts—a single center experience |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917467/ https://www.ncbi.nlm.nih.gov/pubmed/36769783 http://dx.doi.org/10.3390/jcm12031133 |
work_keys_str_mv | AT janasnazeanna modifiedcarnoysversuscarnoyssolutioninthemanagementofodontogenickeratocystsasinglecenterexperience AT zhangwei modifiedcarnoysversuscarnoyssolutioninthemanagementofodontogenickeratocystsasinglecenterexperience AT szutamariusz modifiedcarnoysversuscarnoyssolutioninthemanagementofodontogenickeratocystsasinglecenterexperience |