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Mycobacterium tuberculosis Evasion of Guanylate Binding Protein-Mediated Host Defense in Mice Requires the ESX1 Secretion System

Cell-intrinsic immune mechanisms control intracellular pathogens that infect eukaryotes. The intracellular pathogen Mycobacterium tuberculosis (Mtb) evolved to withstand cell-autonomous immunity to cause persistent infections and disease. A potent inducer of cell-autonomous immunity is the lymphocyt...

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Detalles Bibliográficos
Autores principales: Olive, Andrew J., Smith, Clare M., Baer, Christina E., Coers, Jörn, Sassetti, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917499/
https://www.ncbi.nlm.nih.gov/pubmed/36769182
http://dx.doi.org/10.3390/ijms24032861