Cargando…

Hepatic Glucose Metabolism Disorder Induced by Adipose Tissue-Derived miR-548ag via DPP4 Upregulation

The present study aimed to explore the molecular mechanism underlying the regulation of glucose metabolism by miR-548ag. For the first time, we found that miR-548ag expression was elevated in the abdominal adipose tissue and serum of subjects with obesity and type 2 diabetes mellitus (T2DM). The con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chu, Xiaolong, Hou, Yanting, Zhang, Xueting, Li, Menghuan, Ma, Dingling, Tang, Yihan, Yuan, Chenggang, Sun, Chaoyue, Liang, Maodi, Liu, Jie, Wei, Qianqian, Chang, Yongsheng, Wang, Cuizhe, Zhang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917501/ https://www.ncbi.nlm.nih.gov/pubmed/36769291 http://dx.doi.org/10.3390/ijms24032964

Ejemplares similares

miR‐548ag functions as an oncogene by suppressing MOB1B in the development of obesity‐related endometrial cancer
por: Pang, Huai, et al.
Publicado: (2022)

miR‐4431 targets TRIP10/PRKD1 and impairs glucose metabolism
por: Pan, Chongge, et al.
Publicado: (2021)

Caprylic Acid (FFA C8:0) promotes the progression of prostate cancer by up-regulating G protein-coupled receptor 84/ Krüppel-like factor 7
por: Li, Xue, et al.
Publicado: (2023)

Obesity-induced elevated palmitic acid promotes inflammation and glucose metabolism disorders through GPRs/NF-κB/KLF7 pathway
por: Qiu, Tongtong, et al.
Publicado: (2022)

548 Toward a Burn Risk Calculator
por: Bessey, Palmer Q, et al.
Publicado: (2022)

FRI548 A Case Of Periureteric Myxedema
por: Ferris, Jaclyn M, et al.
Publicado: (2023)

PA and OA induce abnormal glucose metabolism by inhibiting KLF15 in adipocytes
por: Wang, Cuizhe, et al.
Publicado: (2021)

The 2,548 best things anybody ever said /
Publicado: (2003)

Abell 548: an x-ray and optical analysis of substructure
por: Davis, D S, et al.
Publicado: (1994)

548 Immunoglobulin a Deficiency, HPV and Oral Cancer
por: Alvarez, Jorge, et al.
Publicado: (2012)

miR-1279, miR-548j, miR-548m, and miR-548d-5p Binding Sites in CDSs of Paralogous and Orthologous PTPN12, MSH6, and ZEB1 Genes
por: Ivashchenko, Anatoliy T., et al.
Publicado: (2013)

Free Fatty Acids Promote the Development of Prostate Cancer by Upregulating Peroxisome Proliferator-Activated Receptor Gamma
por: Ha, Xiaodan, et al.
Publicado: (2020)

DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity
por: Böhm, Anja, et al.
Publicado: (2017)

Hsa-mir-548 family expression in human reproductive tissues
por: Rooda, Ilmatar, et al.
Publicado: (2021)

A rice variation map derived from 10 548 rice accessions reveals the importance of rare variants
por: Wang, Tianyi, et al.
Publicado: (2023)

A nickel and silicon rich phase in irradiated FV548 steel
por: Williams, T M, et al.
Publicado: (1979)

SUN-548 A Case Report on Neonatal Hyperthyroidism Amidst Confusions
por: Sukumaran, Anju, et al.
Publicado: (2019)

548. Convalescent Plasma in Hospitalized Pediatric and Obstetric patients with COVID-19
por: Ikeda, Saki, et al.
Publicado: (2021)

Identification of the DPP-IV Inhibitory Peptides from Donkey Blood and Regulatory Effect on the Gut Microbiota of Type 2 Diabetic Mice
por: Ma, Chaoyue, et al.
Publicado: (2022)

Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes
por: Deacon, Carolyn F.
Publicado: (2019)

Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
por: Fadzeyeva, Evgenia, et al.
Publicado: (2023)

Inverse Agonism of SQ 29,548 and Ramatroban on Thromboxane A2 Receptor
por: Chakraborty, Raja, et al.
Publicado: (2014)

miR-548d-3p inhibits osteosarcoma by downregulating KRAS
por: Chen, Jianhua, et al.
Publicado: (2019)

Enhancement of Thermal Resistance by Metal Ions in Thermotolerant Zymomonas mobilis TISTR 548
por: Kosaka, Tomoyuki, et al.
Publicado: (2020)

ODP548 Fatty acid metabolism-related factors in breast and endometrial cancers
por: Miki, Yasuhiro, et al.
Publicado: (2022)

Hsa_circ_0001666 promotes non-small cell lung cancer migration and invasion through miR-1184/miR-548I/AGO1 axis
por: Wang, Xueting, et al.
Publicado: (2022)

Establishment of a selective evaluation method for DPP4 inhibitors based on recombinant human DPP8 and DPP9 proteins
por: Liu, Jinglong, et al.
Publicado: (2014)

Sequence-based mutation patterns at 41 Y chromosomal STRs in 2 548 father–son pairs
por: Liu, Ze, et al.
Publicado: (2023)

Corrigendum: Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes
por: Deacon, Carolyn F.
Publicado: (2019)

Alteration of gut microbiota induced by DPP-4i treatment improves glucose homeostasis
por: Liao, Xiaoyu, et al.
Publicado: (2019)

Potential Effect of DPP-4 Inhibitors Towards Hepatic Diseases and Associated Glucose Intolerance
por: Sharma, Ashwani, et al.
Publicado: (2022)

DPP4 in Diabetes
por: Röhrborn, Diana, et al.
Publicado: (2015)

Genome-Wide Analysis of mir-548 Gene Family Reveals Evolutionary and Functional Implications
por: Liang, Tingming, et al.
Publicado: (2012)

MON-548 The Relationship of Comorbidities to Mortality and Cause of Death in Patients with Differentiated Thyroid Carcinoma
por: Lee, Young Ki, et al.
Publicado: (2019)

miR548ai antagonism attenuates exosome-induced endothelial cell dysfunction
por: Xie, Xiujie, et al.
Publicado: (2021)

miR-548j-5p regulates angiogenesis in peripheral artery disease
por: Lee, Chiu-Yang, et al.
Publicado: (2022)

548 Volatile Sedation in the Burn Intensive Care Unit: A Quality Improvement Initiative
por: Nardi, Julie, et al.
Publicado: (2023)

The Roles of Dipeptidyl Peptidase 4 (DPP4) and DPP4 Inhibitors in Different Lung Diseases: New Evidence
por: Zhang, Tianli, et al.
Publicado: (2021)

SAT-548 Quantitative Analysis of the Succinylome in the Thyroid Tissue of High Fat Diet-Induced Hypothyroxinemia in Rats
por: Hu, Baoxiang, et al.
Publicado: (2019)

MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist
por: Sun, Xiaochun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_au2dcth0j1caag69i60k98bh7k