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Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience
Introduction: Antegrade sclerotherapy (Tauber) effectively treats varicocele. However, fluoroscopy exposes young males to ionizing radiation. We aimed to evaluate radiation exposure and surgical outcomes after the Tauber procedure. Materials and methods: We retrospectively analysed data from 251 pat...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917517/ https://www.ncbi.nlm.nih.gov/pubmed/36769404 http://dx.doi.org/10.3390/jcm12030755 |
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author | Bebi, Carolina Bilato, Marco Minoli, Dario Guido De Marco, Erika Adalgisa Gnech, Michele Paraboschi, Irene Boeri, Luca Fulgheri, Irene Brambilla, Roberto Campoleoni, Mauro Albo, Giancarlo Montanari, Emanuele Manzoni, Gianantonio Berrettini, Alfredo |
author_facet | Bebi, Carolina Bilato, Marco Minoli, Dario Guido De Marco, Erika Adalgisa Gnech, Michele Paraboschi, Irene Boeri, Luca Fulgheri, Irene Brambilla, Roberto Campoleoni, Mauro Albo, Giancarlo Montanari, Emanuele Manzoni, Gianantonio Berrettini, Alfredo |
author_sort | Bebi, Carolina |
collection | PubMed |
description | Introduction: Antegrade sclerotherapy (Tauber) effectively treats varicocele. However, fluoroscopy exposes young males to ionizing radiation. We aimed to evaluate radiation exposure and surgical outcomes after the Tauber procedure. Materials and methods: We retrospectively analysed data from 251 patients. Dose area product (DAP) and fluoroscopy time were recorded. The effective dose was calculated with the PCXMC software. Descriptive statistics and linear regression tested the association between clinical predictors and radiation exposure. Results: Median (IQR) age and body mass index (BMI) were 14 (13–16) years and 20.1 (17.9–21.6) kg/m². Five (2.1%) patients developed clinical recurrence and two (0.81%) developed complications. Median fluoroscopy time and DAP were 38.5 (27.7–54.0) s and 89.6 (62.5–143.9) cGy*cm(2). The effective dose was 0.19 (0.14–0.31) mSv. Fluoroscopy time was higher in patients with collateral veins (41 (26–49) s vs. 36 (31–61) s, p = 0.02). The median amount of sclerosing agent (SA) used was 3 (3–4) ml. DAP was higher when SA > 3 mL was used (101.4 (65–183) cGy*cm(2) vs. 80.5 (59–119) cGy*cm(2); p < 0.01). At univariable linear regression, age, BMI, operative time and SA > 3 mL were associated with higher DAP (all p < 0.01). At multivariable linear regression, only BMI (beta 12.9, p < 0.001) and operative time (beta 1.9, p < 0.01) emerged as predictors of higher DAP, after accounting for age and SA > 3 mL. Conclusions: The Tauber procedure is safe and associated with low effective doses. Operative time and the patient’s BMI independently predict a higher radiation dose. |
format | Online Article Text |
id | pubmed-9917517 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99175172023-02-11 Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience Bebi, Carolina Bilato, Marco Minoli, Dario Guido De Marco, Erika Adalgisa Gnech, Michele Paraboschi, Irene Boeri, Luca Fulgheri, Irene Brambilla, Roberto Campoleoni, Mauro Albo, Giancarlo Montanari, Emanuele Manzoni, Gianantonio Berrettini, Alfredo J Clin Med Article Introduction: Antegrade sclerotherapy (Tauber) effectively treats varicocele. However, fluoroscopy exposes young males to ionizing radiation. We aimed to evaluate radiation exposure and surgical outcomes after the Tauber procedure. Materials and methods: We retrospectively analysed data from 251 patients. Dose area product (DAP) and fluoroscopy time were recorded. The effective dose was calculated with the PCXMC software. Descriptive statistics and linear regression tested the association between clinical predictors and radiation exposure. Results: Median (IQR) age and body mass index (BMI) were 14 (13–16) years and 20.1 (17.9–21.6) kg/m². Five (2.1%) patients developed clinical recurrence and two (0.81%) developed complications. Median fluoroscopy time and DAP were 38.5 (27.7–54.0) s and 89.6 (62.5–143.9) cGy*cm(2). The effective dose was 0.19 (0.14–0.31) mSv. Fluoroscopy time was higher in patients with collateral veins (41 (26–49) s vs. 36 (31–61) s, p = 0.02). The median amount of sclerosing agent (SA) used was 3 (3–4) ml. DAP was higher when SA > 3 mL was used (101.4 (65–183) cGy*cm(2) vs. 80.5 (59–119) cGy*cm(2); p < 0.01). At univariable linear regression, age, BMI, operative time and SA > 3 mL were associated with higher DAP (all p < 0.01). At multivariable linear regression, only BMI (beta 12.9, p < 0.001) and operative time (beta 1.9, p < 0.01) emerged as predictors of higher DAP, after accounting for age and SA > 3 mL. Conclusions: The Tauber procedure is safe and associated with low effective doses. Operative time and the patient’s BMI independently predict a higher radiation dose. MDPI 2023-01-18 /pmc/articles/PMC9917517/ /pubmed/36769404 http://dx.doi.org/10.3390/jcm12030755 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bebi, Carolina Bilato, Marco Minoli, Dario Guido De Marco, Erika Adalgisa Gnech, Michele Paraboschi, Irene Boeri, Luca Fulgheri, Irene Brambilla, Roberto Campoleoni, Mauro Albo, Giancarlo Montanari, Emanuele Manzoni, Gianantonio Berrettini, Alfredo Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience |
title | Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience |
title_full | Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience |
title_fullStr | Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience |
title_full_unstemmed | Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience |
title_short | Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience |
title_sort | radiation exposure and surgical outcomes after antegrade sclerotherapy for the treatment of varicocele in the paediatric population: a single centre experience |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917517/ https://www.ncbi.nlm.nih.gov/pubmed/36769404 http://dx.doi.org/10.3390/jcm12030755 |
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