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Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience

Introduction: Antegrade sclerotherapy (Tauber) effectively treats varicocele. However, fluoroscopy exposes young males to ionizing radiation. We aimed to evaluate radiation exposure and surgical outcomes after the Tauber procedure. Materials and methods: We retrospectively analysed data from 251 pat...

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Autores principales: Bebi, Carolina, Bilato, Marco, Minoli, Dario Guido, De Marco, Erika Adalgisa, Gnech, Michele, Paraboschi, Irene, Boeri, Luca, Fulgheri, Irene, Brambilla, Roberto, Campoleoni, Mauro, Albo, Giancarlo, Montanari, Emanuele, Manzoni, Gianantonio, Berrettini, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917517/
https://www.ncbi.nlm.nih.gov/pubmed/36769404
http://dx.doi.org/10.3390/jcm12030755
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author Bebi, Carolina
Bilato, Marco
Minoli, Dario Guido
De Marco, Erika Adalgisa
Gnech, Michele
Paraboschi, Irene
Boeri, Luca
Fulgheri, Irene
Brambilla, Roberto
Campoleoni, Mauro
Albo, Giancarlo
Montanari, Emanuele
Manzoni, Gianantonio
Berrettini, Alfredo
author_facet Bebi, Carolina
Bilato, Marco
Minoli, Dario Guido
De Marco, Erika Adalgisa
Gnech, Michele
Paraboschi, Irene
Boeri, Luca
Fulgheri, Irene
Brambilla, Roberto
Campoleoni, Mauro
Albo, Giancarlo
Montanari, Emanuele
Manzoni, Gianantonio
Berrettini, Alfredo
author_sort Bebi, Carolina
collection PubMed
description Introduction: Antegrade sclerotherapy (Tauber) effectively treats varicocele. However, fluoroscopy exposes young males to ionizing radiation. We aimed to evaluate radiation exposure and surgical outcomes after the Tauber procedure. Materials and methods: We retrospectively analysed data from 251 patients. Dose area product (DAP) and fluoroscopy time were recorded. The effective dose was calculated with the PCXMC software. Descriptive statistics and linear regression tested the association between clinical predictors and radiation exposure. Results: Median (IQR) age and body mass index (BMI) were 14 (13–16) years and 20.1 (17.9–21.6) kg/m². Five (2.1%) patients developed clinical recurrence and two (0.81%) developed complications. Median fluoroscopy time and DAP were 38.5 (27.7–54.0) s and 89.6 (62.5–143.9) cGy*cm(2). The effective dose was 0.19 (0.14–0.31) mSv. Fluoroscopy time was higher in patients with collateral veins (41 (26–49) s vs. 36 (31–61) s, p = 0.02). The median amount of sclerosing agent (SA) used was 3 (3–4) ml. DAP was higher when SA > 3 mL was used (101.4 (65–183) cGy*cm(2) vs. 80.5 (59–119) cGy*cm(2); p < 0.01). At univariable linear regression, age, BMI, operative time and SA > 3 mL were associated with higher DAP (all p < 0.01). At multivariable linear regression, only BMI (beta 12.9, p < 0.001) and operative time (beta 1.9, p < 0.01) emerged as predictors of higher DAP, after accounting for age and SA > 3 mL. Conclusions: The Tauber procedure is safe and associated with low effective doses. Operative time and the patient’s BMI independently predict a higher radiation dose.
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spelling pubmed-99175172023-02-11 Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience Bebi, Carolina Bilato, Marco Minoli, Dario Guido De Marco, Erika Adalgisa Gnech, Michele Paraboschi, Irene Boeri, Luca Fulgheri, Irene Brambilla, Roberto Campoleoni, Mauro Albo, Giancarlo Montanari, Emanuele Manzoni, Gianantonio Berrettini, Alfredo J Clin Med Article Introduction: Antegrade sclerotherapy (Tauber) effectively treats varicocele. However, fluoroscopy exposes young males to ionizing radiation. We aimed to evaluate radiation exposure and surgical outcomes after the Tauber procedure. Materials and methods: We retrospectively analysed data from 251 patients. Dose area product (DAP) and fluoroscopy time were recorded. The effective dose was calculated with the PCXMC software. Descriptive statistics and linear regression tested the association between clinical predictors and radiation exposure. Results: Median (IQR) age and body mass index (BMI) were 14 (13–16) years and 20.1 (17.9–21.6) kg/m². Five (2.1%) patients developed clinical recurrence and two (0.81%) developed complications. Median fluoroscopy time and DAP were 38.5 (27.7–54.0) s and 89.6 (62.5–143.9) cGy*cm(2). The effective dose was 0.19 (0.14–0.31) mSv. Fluoroscopy time was higher in patients with collateral veins (41 (26–49) s vs. 36 (31–61) s, p = 0.02). The median amount of sclerosing agent (SA) used was 3 (3–4) ml. DAP was higher when SA > 3 mL was used (101.4 (65–183) cGy*cm(2) vs. 80.5 (59–119) cGy*cm(2); p < 0.01). At univariable linear regression, age, BMI, operative time and SA > 3 mL were associated with higher DAP (all p < 0.01). At multivariable linear regression, only BMI (beta 12.9, p < 0.001) and operative time (beta 1.9, p < 0.01) emerged as predictors of higher DAP, after accounting for age and SA > 3 mL. Conclusions: The Tauber procedure is safe and associated with low effective doses. Operative time and the patient’s BMI independently predict a higher radiation dose. MDPI 2023-01-18 /pmc/articles/PMC9917517/ /pubmed/36769404 http://dx.doi.org/10.3390/jcm12030755 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bebi, Carolina
Bilato, Marco
Minoli, Dario Guido
De Marco, Erika Adalgisa
Gnech, Michele
Paraboschi, Irene
Boeri, Luca
Fulgheri, Irene
Brambilla, Roberto
Campoleoni, Mauro
Albo, Giancarlo
Montanari, Emanuele
Manzoni, Gianantonio
Berrettini, Alfredo
Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience
title Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience
title_full Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience
title_fullStr Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience
title_full_unstemmed Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience
title_short Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience
title_sort radiation exposure and surgical outcomes after antegrade sclerotherapy for the treatment of varicocele in the paediatric population: a single centre experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917517/
https://www.ncbi.nlm.nih.gov/pubmed/36769404
http://dx.doi.org/10.3390/jcm12030755
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