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Validation of the Fast-Track Model: A Simple Tool to Assess the Severity of Diabetic Foot Ulcers

This study aimed to validate the association between the grades of severity of diabetic foot ulcers (DFUs) identified by the fast-tack model and specific outcomes. Three hundred and sixty-seven patients with new DFUs who were referred to a tertiary level diabetic foot service serving Rome, Italy, we...

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Autores principales: Meloni, Marco, Bouillet, Benjamin, Ahluwalia, Raju, Sanchez-Rios, Juan Pedro, Iacopi, Elisabetta, Izzo, Valentina, Manu, Chris, Julien, Vouillarmet, Luedmann, Claas, Garcia-Klepzig, José Luis, Guillaumat, Jérome, Lazaro-Martinez, Jose Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917528/
https://www.ncbi.nlm.nih.gov/pubmed/36769408
http://dx.doi.org/10.3390/jcm12030761
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author Meloni, Marco
Bouillet, Benjamin
Ahluwalia, Raju
Sanchez-Rios, Juan Pedro
Iacopi, Elisabetta
Izzo, Valentina
Manu, Chris
Julien, Vouillarmet
Luedmann, Claas
Garcia-Klepzig, José Luis
Guillaumat, Jérome
Lazaro-Martinez, Jose Luis
author_facet Meloni, Marco
Bouillet, Benjamin
Ahluwalia, Raju
Sanchez-Rios, Juan Pedro
Iacopi, Elisabetta
Izzo, Valentina
Manu, Chris
Julien, Vouillarmet
Luedmann, Claas
Garcia-Klepzig, José Luis
Guillaumat, Jérome
Lazaro-Martinez, Jose Luis
author_sort Meloni, Marco
collection PubMed
description This study aimed to validate the association between the grades of severity of diabetic foot ulcers (DFUs) identified by the fast-tack model and specific outcomes. Three hundred and sixty-seven patients with new DFUs who were referred to a tertiary level diabetic foot service serving Rome, Italy, were included. The fast-track model identifies three levels of DFUs’ severity: uncomplicated DFUs, including superficial wounds, not-infected wounds, and not-ischemic wounds; complicated DFUs, including ischemic wounds, infected wounds, and deep ulcers involving the muscles, tendons, or bones, and any kind of ulcers in patients on dialysis and/or with heart failure; and severely complicated DFUs, including abscesses, wet gangrene, necrotizing fasciitis, fever, or clinical signs of sepsis. Healing, minor and major amputation, hospitalization, and survival after 24 weeks of follow-up were considered. Among the included patients, 35 (9.6%) had uncomplicated DFUs, 210 (57.2%) had complicated DFUs, and 122 (33.2%) had severely complicated DFUs. The outcomes for patients with uncomplicated, complicated, and severely complicated DFUs were as follows, respectively: healing, 97.1%, 86.2%, and 69.8%; minor amputation, 2.9%, 20%, and 66.4%; major amputation, 0%, 2.9%, and 16.4%; hospitalization, 14.3%, 55.7%, and 89.3%; survival, 100%, 96.7%, and 89.3%. DFU severity was an independent predictor of healing, amputation, hospitalization, and survival. The current study shows an association between the grade of severity of DFUs identified by the fast-track model and the considered outcomes. The fast-track model may be a useful tool for assessing the severity and prognosis of DFUs.
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spelling pubmed-99175282023-02-11 Validation of the Fast-Track Model: A Simple Tool to Assess the Severity of Diabetic Foot Ulcers Meloni, Marco Bouillet, Benjamin Ahluwalia, Raju Sanchez-Rios, Juan Pedro Iacopi, Elisabetta Izzo, Valentina Manu, Chris Julien, Vouillarmet Luedmann, Claas Garcia-Klepzig, José Luis Guillaumat, Jérome Lazaro-Martinez, Jose Luis J Clin Med Article This study aimed to validate the association between the grades of severity of diabetic foot ulcers (DFUs) identified by the fast-tack model and specific outcomes. Three hundred and sixty-seven patients with new DFUs who were referred to a tertiary level diabetic foot service serving Rome, Italy, were included. The fast-track model identifies three levels of DFUs’ severity: uncomplicated DFUs, including superficial wounds, not-infected wounds, and not-ischemic wounds; complicated DFUs, including ischemic wounds, infected wounds, and deep ulcers involving the muscles, tendons, or bones, and any kind of ulcers in patients on dialysis and/or with heart failure; and severely complicated DFUs, including abscesses, wet gangrene, necrotizing fasciitis, fever, or clinical signs of sepsis. Healing, minor and major amputation, hospitalization, and survival after 24 weeks of follow-up were considered. Among the included patients, 35 (9.6%) had uncomplicated DFUs, 210 (57.2%) had complicated DFUs, and 122 (33.2%) had severely complicated DFUs. The outcomes for patients with uncomplicated, complicated, and severely complicated DFUs were as follows, respectively: healing, 97.1%, 86.2%, and 69.8%; minor amputation, 2.9%, 20%, and 66.4%; major amputation, 0%, 2.9%, and 16.4%; hospitalization, 14.3%, 55.7%, and 89.3%; survival, 100%, 96.7%, and 89.3%. DFU severity was an independent predictor of healing, amputation, hospitalization, and survival. The current study shows an association between the grade of severity of DFUs identified by the fast-track model and the considered outcomes. The fast-track model may be a useful tool for assessing the severity and prognosis of DFUs. MDPI 2023-01-18 /pmc/articles/PMC9917528/ /pubmed/36769408 http://dx.doi.org/10.3390/jcm12030761 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Meloni, Marco
Bouillet, Benjamin
Ahluwalia, Raju
Sanchez-Rios, Juan Pedro
Iacopi, Elisabetta
Izzo, Valentina
Manu, Chris
Julien, Vouillarmet
Luedmann, Claas
Garcia-Klepzig, José Luis
Guillaumat, Jérome
Lazaro-Martinez, Jose Luis
Validation of the Fast-Track Model: A Simple Tool to Assess the Severity of Diabetic Foot Ulcers
title Validation of the Fast-Track Model: A Simple Tool to Assess the Severity of Diabetic Foot Ulcers
title_full Validation of the Fast-Track Model: A Simple Tool to Assess the Severity of Diabetic Foot Ulcers
title_fullStr Validation of the Fast-Track Model: A Simple Tool to Assess the Severity of Diabetic Foot Ulcers
title_full_unstemmed Validation of the Fast-Track Model: A Simple Tool to Assess the Severity of Diabetic Foot Ulcers
title_short Validation of the Fast-Track Model: A Simple Tool to Assess the Severity of Diabetic Foot Ulcers
title_sort validation of the fast-track model: a simple tool to assess the severity of diabetic foot ulcers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917528/
https://www.ncbi.nlm.nih.gov/pubmed/36769408
http://dx.doi.org/10.3390/jcm12030761
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