Cargando…

BRG1: Promoter or Suppressor of Cancer? The Outcome of BRG1’s Interaction with Specific Cellular Pathways

BRG1 is one of two catalytic subunits of the SWI/SNF ATP-dependent chromatin-remodeling complex. In cancer, it has been hypothesized that BRG1 acts as a tumor suppressor. Further study has shown that, under certain circumstances, BRG1 acts as an oncogene. Targeted knockout of BRG1 has proven success...

Descripción completa

Detalles Bibliográficos
Autores principales: Shaykevich, Aaron, Silverman, Isaac, Bandyopadhyaya, Gargi, Maitra, Radhashree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917617/
https://www.ncbi.nlm.nih.gov/pubmed/36769189
http://dx.doi.org/10.3390/ijms24032869