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Morbidity Associated with Chronic Hyponatremia

This article will discuss the consequences of chronic hyponatremia. In conditions such as cancer, heart failure, liver cirrhosis, or chronic kidney disease, the presence and magnitude of hypotonic hyponatremia are considered to reflect the severity of the underlying disease and are associated with i...

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Detalles Bibliográficos
Autor principal: Decaux, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917626/
https://www.ncbi.nlm.nih.gov/pubmed/36769626
http://dx.doi.org/10.3390/jcm12030978
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author Decaux, Guy
author_facet Decaux, Guy
author_sort Decaux, Guy
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description This article will discuss the consequences of chronic hyponatremia. In conditions such as cancer, heart failure, liver cirrhosis, or chronic kidney disease, the presence and magnitude of hypotonic hyponatremia are considered to reflect the severity of the underlying disease and are associated with increased morbidity as well as mortality. Hyponatremia can be acute (<48 h) or chronic (>2–3 days). Chronic hyponatremia is associated with attention deficit, dizziness, tiredness, gait disturbance, falls, sarcopenia, bone fractures, osteoporosis, hypercalciuria (in the syndrome of inappropriate antidiuresis—SIADH), and kidney stones. In vitro studies have shown that cells grown in a low concentration of extracellular sodium have a greater proliferation rate and motility. Patients with chronic hyponatremia are more likely to develop cancer. We will not review the clinical consequences of respiratory arrest and osmotic demyelination syndrome (ODS) of the too-late or excessive treatment of hyponatremia.
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spelling pubmed-99176262023-02-11 Morbidity Associated with Chronic Hyponatremia Decaux, Guy J Clin Med Opinion This article will discuss the consequences of chronic hyponatremia. In conditions such as cancer, heart failure, liver cirrhosis, or chronic kidney disease, the presence and magnitude of hypotonic hyponatremia are considered to reflect the severity of the underlying disease and are associated with increased morbidity as well as mortality. Hyponatremia can be acute (<48 h) or chronic (>2–3 days). Chronic hyponatremia is associated with attention deficit, dizziness, tiredness, gait disturbance, falls, sarcopenia, bone fractures, osteoporosis, hypercalciuria (in the syndrome of inappropriate antidiuresis—SIADH), and kidney stones. In vitro studies have shown that cells grown in a low concentration of extracellular sodium have a greater proliferation rate and motility. Patients with chronic hyponatremia are more likely to develop cancer. We will not review the clinical consequences of respiratory arrest and osmotic demyelination syndrome (ODS) of the too-late or excessive treatment of hyponatremia. MDPI 2023-01-27 /pmc/articles/PMC9917626/ /pubmed/36769626 http://dx.doi.org/10.3390/jcm12030978 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Opinion
Decaux, Guy
Morbidity Associated with Chronic Hyponatremia
title Morbidity Associated with Chronic Hyponatremia
title_full Morbidity Associated with Chronic Hyponatremia
title_fullStr Morbidity Associated with Chronic Hyponatremia
title_full_unstemmed Morbidity Associated with Chronic Hyponatremia
title_short Morbidity Associated with Chronic Hyponatremia
title_sort morbidity associated with chronic hyponatremia
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917626/
https://www.ncbi.nlm.nih.gov/pubmed/36769626
http://dx.doi.org/10.3390/jcm12030978
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