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Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin–Toxin Fusion in a Pancreatic Cancer Xenograft Model

Pancreatic cancer (PC) is one of the most aggressive malignancies. A combination of targeted therapies could increase the therapeutic efficacy in tumors with heterogeneous target expression. Overexpression of the human epidermal growth factor receptor type 3 (HER3) and the epithelial cell adhesion m...

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Detalles Bibliográficos
Autores principales: Xu, Tianqi, Schulga, Alexey, Konovalova, Elena, Rinne, Sara S., Zhang, Hongchao, Vorontsova, Olga, Orlova, Anna, Deyev, Sergey M., Tolmachev, Vladimir, Vorobyeva, Anzhelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917732/
https://www.ncbi.nlm.nih.gov/pubmed/36769161
http://dx.doi.org/10.3390/ijms24032838