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Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin–Toxin Fusion in a Pancreatic Cancer Xenograft Model
Pancreatic cancer (PC) is one of the most aggressive malignancies. A combination of targeted therapies could increase the therapeutic efficacy in tumors with heterogeneous target expression. Overexpression of the human epidermal growth factor receptor type 3 (HER3) and the epithelial cell adhesion m...
Autores principales: | Xu, Tianqi, Schulga, Alexey, Konovalova, Elena, Rinne, Sara S., Zhang, Hongchao, Vorontsova, Olga, Orlova, Anna, Deyev, Sergey M., Tolmachev, Vladimir, Vorobyeva, Anzhelika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917732/ https://www.ncbi.nlm.nih.gov/pubmed/36769161 http://dx.doi.org/10.3390/ijms24032838 |
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