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Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study

Tinnitus is a common symptom reported in otolaryngologic practice. Although the pathophysiology of tinnitus has not been fully understood, clinical studies suggest that psychological symptoms of depression, anxiety, and somatization are increased in tinnitus patients. However, patients seeking medic...

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Autores principales: Hackenberg, Berit, Döge, Julia, O’Brien, Karoline, Bohnert, Andrea, Lackner, Karl J., Beutel, Manfred E., Michal, Matthias, Münzel, Thomas, Wild, Philipp S., Pfeiffer, Norbert, Schulz, Andreas, Schmidtmann, Irene, Matthias, Christoph, Bahr, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917824/
https://www.ncbi.nlm.nih.gov/pubmed/36769823
http://dx.doi.org/10.3390/jcm12031169
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author Hackenberg, Berit
Döge, Julia
O’Brien, Karoline
Bohnert, Andrea
Lackner, Karl J.
Beutel, Manfred E.
Michal, Matthias
Münzel, Thomas
Wild, Philipp S.
Pfeiffer, Norbert
Schulz, Andreas
Schmidtmann, Irene
Matthias, Christoph
Bahr, Katharina
author_facet Hackenberg, Berit
Döge, Julia
O’Brien, Karoline
Bohnert, Andrea
Lackner, Karl J.
Beutel, Manfred E.
Michal, Matthias
Münzel, Thomas
Wild, Philipp S.
Pfeiffer, Norbert
Schulz, Andreas
Schmidtmann, Irene
Matthias, Christoph
Bahr, Katharina
author_sort Hackenberg, Berit
collection PubMed
description Tinnitus is a common symptom reported in otolaryngologic practice. Although the pathophysiology of tinnitus has not been fully understood, clinical studies suggest that psychological symptoms of depression, anxiety, and somatization are increased in tinnitus patients. However, patients seeking medical treatment for tinnitus may be especially vulnerable. Population-based studies reporting on the association between tinnitus and psychological distress are still lacking. The aim of this study was to investigate the correlation of tinnitus with depression, anxiety, or somatization in a large population-based cohort. The Gutenberg Health Study is a population-based cohort study. Participants were asked about the occurrence of tinnitus (yes/no) and how much they were bothered by it. In addition, they completed the PHQ-9, GAD-7, and SSS-8 questionnaires to assess depressive symptoms, anxiety, and somatic symptom disorders. A total of 8539 participants were included in the study cohort. Tinnitus prevalence was 28.0% (2387). The prevalence of depression/anxiety/somatic symptom disorders was significantly higher among participants with tinnitus than among participants without tinnitus (7.9%/5.4%/40.4% participants with tinnitus vs. 4.6%/3.3%/26.9% participants without tinnitus, p-value < 0.0001). Logistic regression results showed that participants with tinnitus were more likely to suffer from depression (OR = 2.033, 95% CI [1.584; 2.601], p-value < 0.0001), anxiety (OR = 1.841, 95% CI [1.228; 2.728], p-value = 0.0027), or somatic symptom disorders (OR = 2.057, 95% CI [1.799; 2.352], p-value < 0.0001). Symptoms of depression, anxiety, and somatic symptom disorders were increased in participants with tinnitus. This must be taken into account when treating these patients.
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spelling pubmed-99178242023-02-11 Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study Hackenberg, Berit Döge, Julia O’Brien, Karoline Bohnert, Andrea Lackner, Karl J. Beutel, Manfred E. Michal, Matthias Münzel, Thomas Wild, Philipp S. Pfeiffer, Norbert Schulz, Andreas Schmidtmann, Irene Matthias, Christoph Bahr, Katharina J Clin Med Article Tinnitus is a common symptom reported in otolaryngologic practice. Although the pathophysiology of tinnitus has not been fully understood, clinical studies suggest that psychological symptoms of depression, anxiety, and somatization are increased in tinnitus patients. However, patients seeking medical treatment for tinnitus may be especially vulnerable. Population-based studies reporting on the association between tinnitus and psychological distress are still lacking. The aim of this study was to investigate the correlation of tinnitus with depression, anxiety, or somatization in a large population-based cohort. The Gutenberg Health Study is a population-based cohort study. Participants were asked about the occurrence of tinnitus (yes/no) and how much they were bothered by it. In addition, they completed the PHQ-9, GAD-7, and SSS-8 questionnaires to assess depressive symptoms, anxiety, and somatic symptom disorders. A total of 8539 participants were included in the study cohort. Tinnitus prevalence was 28.0% (2387). The prevalence of depression/anxiety/somatic symptom disorders was significantly higher among participants with tinnitus than among participants without tinnitus (7.9%/5.4%/40.4% participants with tinnitus vs. 4.6%/3.3%/26.9% participants without tinnitus, p-value < 0.0001). Logistic regression results showed that participants with tinnitus were more likely to suffer from depression (OR = 2.033, 95% CI [1.584; 2.601], p-value < 0.0001), anxiety (OR = 1.841, 95% CI [1.228; 2.728], p-value = 0.0027), or somatic symptom disorders (OR = 2.057, 95% CI [1.799; 2.352], p-value < 0.0001). Symptoms of depression, anxiety, and somatic symptom disorders were increased in participants with tinnitus. This must be taken into account when treating these patients. MDPI 2023-02-01 /pmc/articles/PMC9917824/ /pubmed/36769823 http://dx.doi.org/10.3390/jcm12031169 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hackenberg, Berit
Döge, Julia
O’Brien, Karoline
Bohnert, Andrea
Lackner, Karl J.
Beutel, Manfred E.
Michal, Matthias
Münzel, Thomas
Wild, Philipp S.
Pfeiffer, Norbert
Schulz, Andreas
Schmidtmann, Irene
Matthias, Christoph
Bahr, Katharina
Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study
title Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study
title_full Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study
title_fullStr Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study
title_full_unstemmed Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study
title_short Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study
title_sort tinnitus and its relation to depression, anxiety, and stress—a population-based cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917824/
https://www.ncbi.nlm.nih.gov/pubmed/36769823
http://dx.doi.org/10.3390/jcm12031169
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