Interfering with the Ubiquitin-Mediated Regulation of Akt as a Strategy for Cancer Treatment

The serine/threonine kinase Akt modulates the functions of numerous substrates, many of them being involved in cell proliferation and growth, metabolism, angiogenesis, resistance to hypoxia and migration. Akt is frequently deregulated in many types of human cancers, its overexpression or abnormal ac...

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Detalles Bibliográficos
Autores principales: Paccosi, Elena, Balzerano, Alessio, Proietti-De-Santis, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917864/
https://www.ncbi.nlm.nih.gov/pubmed/36769122
http://dx.doi.org/10.3390/ijms24032809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917864/
https://www.ncbi.nlm.nih.gov/pubmed/36769122
http://dx.doi.org/10.3390/ijms24032809

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