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Interfering with the Ubiquitin-Mediated Regulation of Akt as a Strategy for Cancer Treatment
The serine/threonine kinase Akt modulates the functions of numerous substrates, many of them being involved in cell proliferation and growth, metabolism, angiogenesis, resistance to hypoxia and migration. Akt is frequently deregulated in many types of human cancers, its overexpression or abnormal ac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917864/ https://www.ncbi.nlm.nih.gov/pubmed/36769122 http://dx.doi.org/10.3390/ijms24032809 |