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Ultrasonography Measurement of Renal Dimension and Its Correlation with Age, Body Indices, and eGFR in Type 1 Diabetes Mellitus Patients: Real World Data in Taiwan

Background: Assessment of renal size is clinically significant for the screening, diagnosis, and follow-up of renal diseases as the basis of clinical decisions. However, the relationship of renal dimension with age, body indices, and the estimated glomerular filtration rate (eGFR) has rarely been re...

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Autores principales: Su, Hsuan-An, Chen, Jung-Fu, Fu, Chung-Ming, Lee, Yueh-Ting, Wang, Yi, Huang, Chiang-Chi, Chen, Jin-Bor, Lee, Chien-Te, Wu, Chien-Hsing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917872/
https://www.ncbi.nlm.nih.gov/pubmed/36769758
http://dx.doi.org/10.3390/jcm12031109
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author Su, Hsuan-An
Chen, Jung-Fu
Fu, Chung-Ming
Lee, Yueh-Ting
Wang, Yi
Huang, Chiang-Chi
Chen, Jin-Bor
Lee, Chien-Te
Wu, Chien-Hsing
author_facet Su, Hsuan-An
Chen, Jung-Fu
Fu, Chung-Ming
Lee, Yueh-Ting
Wang, Yi
Huang, Chiang-Chi
Chen, Jin-Bor
Lee, Chien-Te
Wu, Chien-Hsing
author_sort Su, Hsuan-An
collection PubMed
description Background: Assessment of renal size is clinically significant for the screening, diagnosis, and follow-up of renal diseases as the basis of clinical decisions. However, the relationship of renal dimension with age, body indices, and the estimated glomerular filtration rate (eGFR) has rarely been reported in the Chinese type 1 diabetes mellitus (T1DM) population. Methods: A total of 220 T1DM patients were retrospectively analyzed from the Chang Gung Research Database in Taiwan. Demographic data, laboratory data, and ultrasonographic images from January 2001 to November 2018 were extracted. Results: Eighty-five participants (38.6%) were male. The mean age was 34.2 years. The median eGFR was 60.0 mL/min/1.73 m(2). The mean ultrasonographic left and right renal lengths (LL and RL) with S.D. were 10.9 ± 1.5 cm and 11.0 ± 1.1 cm, respectively. Renal lengths were longer with increasing body height and body weight but shorter with increasing age in patients with T1DM. In trajectory analysis, a linear mixed model revealed no significant trend in the changes in eGFR during the follow-up period. Moreover, renal length did not play a significant role in predicting KDIGO CKD stage 5 in the cohort. Conclusions: Renal length and its comparison to the reference ranges demonstrated very limited advantages in predicting renal function decline in T1DM patients.
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spelling pubmed-99178722023-02-11 Ultrasonography Measurement of Renal Dimension and Its Correlation with Age, Body Indices, and eGFR in Type 1 Diabetes Mellitus Patients: Real World Data in Taiwan Su, Hsuan-An Chen, Jung-Fu Fu, Chung-Ming Lee, Yueh-Ting Wang, Yi Huang, Chiang-Chi Chen, Jin-Bor Lee, Chien-Te Wu, Chien-Hsing J Clin Med Article Background: Assessment of renal size is clinically significant for the screening, diagnosis, and follow-up of renal diseases as the basis of clinical decisions. However, the relationship of renal dimension with age, body indices, and the estimated glomerular filtration rate (eGFR) has rarely been reported in the Chinese type 1 diabetes mellitus (T1DM) population. Methods: A total of 220 T1DM patients were retrospectively analyzed from the Chang Gung Research Database in Taiwan. Demographic data, laboratory data, and ultrasonographic images from January 2001 to November 2018 were extracted. Results: Eighty-five participants (38.6%) were male. The mean age was 34.2 years. The median eGFR was 60.0 mL/min/1.73 m(2). The mean ultrasonographic left and right renal lengths (LL and RL) with S.D. were 10.9 ± 1.5 cm and 11.0 ± 1.1 cm, respectively. Renal lengths were longer with increasing body height and body weight but shorter with increasing age in patients with T1DM. In trajectory analysis, a linear mixed model revealed no significant trend in the changes in eGFR during the follow-up period. Moreover, renal length did not play a significant role in predicting KDIGO CKD stage 5 in the cohort. Conclusions: Renal length and its comparison to the reference ranges demonstrated very limited advantages in predicting renal function decline in T1DM patients. MDPI 2023-01-31 /pmc/articles/PMC9917872/ /pubmed/36769758 http://dx.doi.org/10.3390/jcm12031109 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Su, Hsuan-An
Chen, Jung-Fu
Fu, Chung-Ming
Lee, Yueh-Ting
Wang, Yi
Huang, Chiang-Chi
Chen, Jin-Bor
Lee, Chien-Te
Wu, Chien-Hsing
Ultrasonography Measurement of Renal Dimension and Its Correlation with Age, Body Indices, and eGFR in Type 1 Diabetes Mellitus Patients: Real World Data in Taiwan
title Ultrasonography Measurement of Renal Dimension and Its Correlation with Age, Body Indices, and eGFR in Type 1 Diabetes Mellitus Patients: Real World Data in Taiwan
title_full Ultrasonography Measurement of Renal Dimension and Its Correlation with Age, Body Indices, and eGFR in Type 1 Diabetes Mellitus Patients: Real World Data in Taiwan
title_fullStr Ultrasonography Measurement of Renal Dimension and Its Correlation with Age, Body Indices, and eGFR in Type 1 Diabetes Mellitus Patients: Real World Data in Taiwan
title_full_unstemmed Ultrasonography Measurement of Renal Dimension and Its Correlation with Age, Body Indices, and eGFR in Type 1 Diabetes Mellitus Patients: Real World Data in Taiwan
title_short Ultrasonography Measurement of Renal Dimension and Its Correlation with Age, Body Indices, and eGFR in Type 1 Diabetes Mellitus Patients: Real World Data in Taiwan
title_sort ultrasonography measurement of renal dimension and its correlation with age, body indices, and egfr in type 1 diabetes mellitus patients: real world data in taiwan
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917872/
https://www.ncbi.nlm.nih.gov/pubmed/36769758
http://dx.doi.org/10.3390/jcm12031109
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