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Stable Enzymatic Nanoparticles from Nucleases, Proteases, Lipase and Antioxidant Proteins with Substrate-Binding and Catalytic Properties

Limited membrane permeability and biodegradation hamper the intracellular delivery of the free natural or recombinant enzymes necessary for compensatory therapy. Nanoparticles (NP) provide relative protein stability and unspecific endocytosis-mediated cellular uptake. Our objective was the fabricati...

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Detalles Bibliográficos
Autores principales: Morozova, Olga V., Barinov, Nikolay A., Klinov, Dmitry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917993/
https://www.ncbi.nlm.nih.gov/pubmed/36769367
http://dx.doi.org/10.3390/ijms24033043