Protective Effect of Avenanthramide-C on Auditory Hair Cells against Oxidative Stress, Inflammatory Cytokines, and DNA Damage in Cisplatin-Induced Ototoxicity

Cisplatin-induced ototoxicity leads to hearing impairment, possibly through reactive oxygen species (ROS) production and DNA damage in cochlear hair cells (HC), although the exact mechanism is unknown. Avenanthramide-C (AVN-C), a natural, potent antioxidant, was evaluated in three study groups of no...

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Detalles Bibliográficos
Autores principales: Umugire, Alphonse, Nam, Yoon Seok, Nam, Ye Eun, Choi, Young Mi, Choi, Se Myeong, Lee, Sungsu, Cho, Jong Hyun, Cho, Hyong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918115/
https://www.ncbi.nlm.nih.gov/pubmed/36769271
http://dx.doi.org/10.3390/ijms24032947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918115/
https://www.ncbi.nlm.nih.gov/pubmed/36769271
http://dx.doi.org/10.3390/ijms24032947

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