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Does Post-COVID-19 Erectile Dysfunction Improve over Time?

Background: Some studies have shown that there may be an increase in the frequency of erectile dysfunction after COVID-19. However, no long-term study has investigated whether this is permanent or temporary. In this study, we aimed to examine whether there was an increase in the frequency of erectil...

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Autores principales: Gök, Alper, Altan, Mehmet, Doğan, Ahmet Emin, Eraslan, Aşır, Uysal, Fahrettin Şamil, Öztürk, Ufuk, Saguner, Ardan Muammer, İmamoğlu, Muhammet Abdurrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918199/
https://www.ncbi.nlm.nih.gov/pubmed/36769888
http://dx.doi.org/10.3390/jcm12031241
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author Gök, Alper
Altan, Mehmet
Doğan, Ahmet Emin
Eraslan, Aşır
Uysal, Fahrettin Şamil
Öztürk, Ufuk
Saguner, Ardan Muammer
İmamoğlu, Muhammet Abdurrahim
author_facet Gök, Alper
Altan, Mehmet
Doğan, Ahmet Emin
Eraslan, Aşır
Uysal, Fahrettin Şamil
Öztürk, Ufuk
Saguner, Ardan Muammer
İmamoğlu, Muhammet Abdurrahim
author_sort Gök, Alper
collection PubMed
description Background: Some studies have shown that there may be an increase in the frequency of erectile dysfunction after COVID-19. However, no long-term study has investigated whether this is permanent or temporary. In this study, we aimed to examine whether there was an increase in the frequency of erectile dysfunction among individuals with a history of COVID-19, and, if there was, whether their condition improved over time. Materials and methods: In this study, a total of 125 healthy male healthcare workers, 95 with and 30 without a history of COVID-19, were evaluated in terms of erectile function. Four study groups were formed. The first three groups consisted of individuals with a history of COVID-19 confirmed by the polymerase chain reaction (PCR) test at different times, who recovered from the disease (time elapsed since COVID-19 positivity: <6 months for Group 1, 6 to 12 months for Group 2, and >12 months for Group 3). The individuals in Group 4 did not have a history of COVID-19 diagnosis. In order to evaluate the erectile function of the participants, they were asked to complete the five-item International Index of Erectile Function questionnaire (IIEF-5). Then, statistical analyses were performed to evaluate whether there was a difference between the groups in terms of the IIEF-5 scores. Results: There was a statistically significant difference between the groups in terms of the IIEF-5 scores (p < 0.001), and this difference was determined to be caused by the significantly higher IIEF-5 scores of Groups 3 and 4 compared to Group 1 (p = 0.004 and p < 0.001, respectively). In addition, the IIEF-5 score of Group 4 was statistically significantly higher than that of Group 2 (p < 0.001). However, the IIEF-5 scores did not statistically significantly differ between Groups 1 and 2, Groups 2 and 3, and Groups 3 and 4 (p > 0.999, p = 0.204, and p = 0.592, respectively). Conclusion: There may be deterioration in erectile function after COVID-19; however, this tends to improve over time, especially from the first year after active infection. Given that vascular, hormonal, and/or psychogenic factors may lead to the development of erectile dysfunction after COVID-19, we consider that in order to easily manage this process, it is important to determine the underlying cause, initiate appropriate treatment, and inform couples that this situation can be temporary.
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spelling pubmed-99181992023-02-11 Does Post-COVID-19 Erectile Dysfunction Improve over Time? Gök, Alper Altan, Mehmet Doğan, Ahmet Emin Eraslan, Aşır Uysal, Fahrettin Şamil Öztürk, Ufuk Saguner, Ardan Muammer İmamoğlu, Muhammet Abdurrahim J Clin Med Article Background: Some studies have shown that there may be an increase in the frequency of erectile dysfunction after COVID-19. However, no long-term study has investigated whether this is permanent or temporary. In this study, we aimed to examine whether there was an increase in the frequency of erectile dysfunction among individuals with a history of COVID-19, and, if there was, whether their condition improved over time. Materials and methods: In this study, a total of 125 healthy male healthcare workers, 95 with and 30 without a history of COVID-19, were evaluated in terms of erectile function. Four study groups were formed. The first three groups consisted of individuals with a history of COVID-19 confirmed by the polymerase chain reaction (PCR) test at different times, who recovered from the disease (time elapsed since COVID-19 positivity: <6 months for Group 1, 6 to 12 months for Group 2, and >12 months for Group 3). The individuals in Group 4 did not have a history of COVID-19 diagnosis. In order to evaluate the erectile function of the participants, they were asked to complete the five-item International Index of Erectile Function questionnaire (IIEF-5). Then, statistical analyses were performed to evaluate whether there was a difference between the groups in terms of the IIEF-5 scores. Results: There was a statistically significant difference between the groups in terms of the IIEF-5 scores (p < 0.001), and this difference was determined to be caused by the significantly higher IIEF-5 scores of Groups 3 and 4 compared to Group 1 (p = 0.004 and p < 0.001, respectively). In addition, the IIEF-5 score of Group 4 was statistically significantly higher than that of Group 2 (p < 0.001). However, the IIEF-5 scores did not statistically significantly differ between Groups 1 and 2, Groups 2 and 3, and Groups 3 and 4 (p > 0.999, p = 0.204, and p = 0.592, respectively). Conclusion: There may be deterioration in erectile function after COVID-19; however, this tends to improve over time, especially from the first year after active infection. Given that vascular, hormonal, and/or psychogenic factors may lead to the development of erectile dysfunction after COVID-19, we consider that in order to easily manage this process, it is important to determine the underlying cause, initiate appropriate treatment, and inform couples that this situation can be temporary. MDPI 2023-02-03 /pmc/articles/PMC9918199/ /pubmed/36769888 http://dx.doi.org/10.3390/jcm12031241 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gök, Alper
Altan, Mehmet
Doğan, Ahmet Emin
Eraslan, Aşır
Uysal, Fahrettin Şamil
Öztürk, Ufuk
Saguner, Ardan Muammer
İmamoğlu, Muhammet Abdurrahim
Does Post-COVID-19 Erectile Dysfunction Improve over Time?
title Does Post-COVID-19 Erectile Dysfunction Improve over Time?
title_full Does Post-COVID-19 Erectile Dysfunction Improve over Time?
title_fullStr Does Post-COVID-19 Erectile Dysfunction Improve over Time?
title_full_unstemmed Does Post-COVID-19 Erectile Dysfunction Improve over Time?
title_short Does Post-COVID-19 Erectile Dysfunction Improve over Time?
title_sort does post-covid-19 erectile dysfunction improve over time?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918199/
https://www.ncbi.nlm.nih.gov/pubmed/36769888
http://dx.doi.org/10.3390/jcm12031241
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