Cargando…

Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction

We aimed to review the current evidence on surgical and functional outcomes of Transperineal Laser Ablation for LUTS due to BPH. A comprehensive review of the English-language literature was performed using the MEDLINE and Web of Science databases until 1 August 2022, aiming to select studies evalua...

Descripción completa

Detalles Bibliográficos
Autores principales: Sessa, Francesco, Polverino, Paolo, Siena, Giampaolo, Bisegna, Claudio, Lo Re, Mattia, Spatafora, Pietro, Pecoraro, Alessio, Rivetti, Anna, Moscardi, Luisa, Saladino, Marco, Cocci, Andrea, Gacci, Mauro, Li Marzi, Vincenzo, Carini, Marco, Minervini, Andrea, Campi, Riccardo, Serni, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918261/
https://www.ncbi.nlm.nih.gov/pubmed/36769454
http://dx.doi.org/10.3390/jcm12030793
_version_ 1784886570023649280
author Sessa, Francesco
Polverino, Paolo
Siena, Giampaolo
Bisegna, Claudio
Lo Re, Mattia
Spatafora, Pietro
Pecoraro, Alessio
Rivetti, Anna
Moscardi, Luisa
Saladino, Marco
Cocci, Andrea
Gacci, Mauro
Li Marzi, Vincenzo
Carini, Marco
Minervini, Andrea
Campi, Riccardo
Serni, Sergio
author_facet Sessa, Francesco
Polverino, Paolo
Siena, Giampaolo
Bisegna, Claudio
Lo Re, Mattia
Spatafora, Pietro
Pecoraro, Alessio
Rivetti, Anna
Moscardi, Luisa
Saladino, Marco
Cocci, Andrea
Gacci, Mauro
Li Marzi, Vincenzo
Carini, Marco
Minervini, Andrea
Campi, Riccardo
Serni, Sergio
author_sort Sessa, Francesco
collection PubMed
description We aimed to review the current evidence on surgical and functional outcomes of Transperineal Laser Ablation for LUTS due to BPH. A comprehensive review of the English-language literature was performed using the MEDLINE and Web of Science databases until 1 August 2022, aiming to select studies evaluating TPLA for the treatment of LUTS due to BPH. Additional records were found from Google Scholar. Data were extracted and summarized in Tables. An appropriate form was used for qualitative data synthesis. Seven studies were included in the review, with all being single arm, non-comparative studies. In all studies, functional outcomes were evaluated with uroflowmetry parameters and validated questionnaires, showing a promising effectiveness at short- and mid-term follow-up. There is a lack of standardized pathways for preoperative assessment of patients suitable for TPLA, and even the technique itself has been reported with a few nuances. A good safety profile has been reported by all the authors. Although promising results have been reported by different groups, selection criteria for TPLA and few technical nuances regarding the procedure were found to be heterogeneous across the published series that should be standardized in the future. Further research is needed to confirm these findings.
format Online
Article
Text
id pubmed-9918261
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99182612023-02-11 Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction Sessa, Francesco Polverino, Paolo Siena, Giampaolo Bisegna, Claudio Lo Re, Mattia Spatafora, Pietro Pecoraro, Alessio Rivetti, Anna Moscardi, Luisa Saladino, Marco Cocci, Andrea Gacci, Mauro Li Marzi, Vincenzo Carini, Marco Minervini, Andrea Campi, Riccardo Serni, Sergio J Clin Med Review We aimed to review the current evidence on surgical and functional outcomes of Transperineal Laser Ablation for LUTS due to BPH. A comprehensive review of the English-language literature was performed using the MEDLINE and Web of Science databases until 1 August 2022, aiming to select studies evaluating TPLA for the treatment of LUTS due to BPH. Additional records were found from Google Scholar. Data were extracted and summarized in Tables. An appropriate form was used for qualitative data synthesis. Seven studies were included in the review, with all being single arm, non-comparative studies. In all studies, functional outcomes were evaluated with uroflowmetry parameters and validated questionnaires, showing a promising effectiveness at short- and mid-term follow-up. There is a lack of standardized pathways for preoperative assessment of patients suitable for TPLA, and even the technique itself has been reported with a few nuances. A good safety profile has been reported by all the authors. Although promising results have been reported by different groups, selection criteria for TPLA and few technical nuances regarding the procedure were found to be heterogeneous across the published series that should be standardized in the future. Further research is needed to confirm these findings. MDPI 2023-01-19 /pmc/articles/PMC9918261/ /pubmed/36769454 http://dx.doi.org/10.3390/jcm12030793 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sessa, Francesco
Polverino, Paolo
Siena, Giampaolo
Bisegna, Claudio
Lo Re, Mattia
Spatafora, Pietro
Pecoraro, Alessio
Rivetti, Anna
Moscardi, Luisa
Saladino, Marco
Cocci, Andrea
Gacci, Mauro
Li Marzi, Vincenzo
Carini, Marco
Minervini, Andrea
Campi, Riccardo
Serni, Sergio
Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction
title Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction
title_full Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction
title_fullStr Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction
title_full_unstemmed Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction
title_short Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction
title_sort transperineal laser ablation of the prostate (tpla) for lower urinary tract symptoms due to benign prostatic obstruction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918261/
https://www.ncbi.nlm.nih.gov/pubmed/36769454
http://dx.doi.org/10.3390/jcm12030793
work_keys_str_mv AT sessafrancesco transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT polverinopaolo transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT sienagiampaolo transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT bisegnaclaudio transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT loremattia transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT spataforapietro transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT pecoraroalessio transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT rivettianna transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT moscardiluisa transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT saladinomarco transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT cocciandrea transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT gaccimauro transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT limarzivincenzo transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT carinimarco transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT minerviniandrea transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT campiriccardo transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction
AT sernisergio transperineallaserablationoftheprostatetplaforlowerurinarytractsymptomsduetobenignprostaticobstruction