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Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction
We aimed to review the current evidence on surgical and functional outcomes of Transperineal Laser Ablation for LUTS due to BPH. A comprehensive review of the English-language literature was performed using the MEDLINE and Web of Science databases until 1 August 2022, aiming to select studies evalua...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918261/ https://www.ncbi.nlm.nih.gov/pubmed/36769454 http://dx.doi.org/10.3390/jcm12030793 |
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author | Sessa, Francesco Polverino, Paolo Siena, Giampaolo Bisegna, Claudio Lo Re, Mattia Spatafora, Pietro Pecoraro, Alessio Rivetti, Anna Moscardi, Luisa Saladino, Marco Cocci, Andrea Gacci, Mauro Li Marzi, Vincenzo Carini, Marco Minervini, Andrea Campi, Riccardo Serni, Sergio |
author_facet | Sessa, Francesco Polverino, Paolo Siena, Giampaolo Bisegna, Claudio Lo Re, Mattia Spatafora, Pietro Pecoraro, Alessio Rivetti, Anna Moscardi, Luisa Saladino, Marco Cocci, Andrea Gacci, Mauro Li Marzi, Vincenzo Carini, Marco Minervini, Andrea Campi, Riccardo Serni, Sergio |
author_sort | Sessa, Francesco |
collection | PubMed |
description | We aimed to review the current evidence on surgical and functional outcomes of Transperineal Laser Ablation for LUTS due to BPH. A comprehensive review of the English-language literature was performed using the MEDLINE and Web of Science databases until 1 August 2022, aiming to select studies evaluating TPLA for the treatment of LUTS due to BPH. Additional records were found from Google Scholar. Data were extracted and summarized in Tables. An appropriate form was used for qualitative data synthesis. Seven studies were included in the review, with all being single arm, non-comparative studies. In all studies, functional outcomes were evaluated with uroflowmetry parameters and validated questionnaires, showing a promising effectiveness at short- and mid-term follow-up. There is a lack of standardized pathways for preoperative assessment of patients suitable for TPLA, and even the technique itself has been reported with a few nuances. A good safety profile has been reported by all the authors. Although promising results have been reported by different groups, selection criteria for TPLA and few technical nuances regarding the procedure were found to be heterogeneous across the published series that should be standardized in the future. Further research is needed to confirm these findings. |
format | Online Article Text |
id | pubmed-9918261 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99182612023-02-11 Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction Sessa, Francesco Polverino, Paolo Siena, Giampaolo Bisegna, Claudio Lo Re, Mattia Spatafora, Pietro Pecoraro, Alessio Rivetti, Anna Moscardi, Luisa Saladino, Marco Cocci, Andrea Gacci, Mauro Li Marzi, Vincenzo Carini, Marco Minervini, Andrea Campi, Riccardo Serni, Sergio J Clin Med Review We aimed to review the current evidence on surgical and functional outcomes of Transperineal Laser Ablation for LUTS due to BPH. A comprehensive review of the English-language literature was performed using the MEDLINE and Web of Science databases until 1 August 2022, aiming to select studies evaluating TPLA for the treatment of LUTS due to BPH. Additional records were found from Google Scholar. Data were extracted and summarized in Tables. An appropriate form was used for qualitative data synthesis. Seven studies were included in the review, with all being single arm, non-comparative studies. In all studies, functional outcomes were evaluated with uroflowmetry parameters and validated questionnaires, showing a promising effectiveness at short- and mid-term follow-up. There is a lack of standardized pathways for preoperative assessment of patients suitable for TPLA, and even the technique itself has been reported with a few nuances. A good safety profile has been reported by all the authors. Although promising results have been reported by different groups, selection criteria for TPLA and few technical nuances regarding the procedure were found to be heterogeneous across the published series that should be standardized in the future. Further research is needed to confirm these findings. MDPI 2023-01-19 /pmc/articles/PMC9918261/ /pubmed/36769454 http://dx.doi.org/10.3390/jcm12030793 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sessa, Francesco Polverino, Paolo Siena, Giampaolo Bisegna, Claudio Lo Re, Mattia Spatafora, Pietro Pecoraro, Alessio Rivetti, Anna Moscardi, Luisa Saladino, Marco Cocci, Andrea Gacci, Mauro Li Marzi, Vincenzo Carini, Marco Minervini, Andrea Campi, Riccardo Serni, Sergio Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction |
title | Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction |
title_full | Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction |
title_fullStr | Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction |
title_full_unstemmed | Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction |
title_short | Transperineal Laser Ablation of the Prostate (TPLA) for Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction |
title_sort | transperineal laser ablation of the prostate (tpla) for lower urinary tract symptoms due to benign prostatic obstruction |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918261/ https://www.ncbi.nlm.nih.gov/pubmed/36769454 http://dx.doi.org/10.3390/jcm12030793 |
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