Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1

Pancreatic stellate cells (PSCs) are key to the treatment-refractory desmoplastic phenotype of pancreatic ductal adenocarcinoma (PDAC) and have received considerable attention as a stromal target for cancer therapy. This approach demands detailed understanding of their pro- and anti-tumourigenic eff...

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Detalles Bibliográficos
Autores principales: Coetzee, Abigail S., Carter, Edward P., Rodríguez-Fernández, Lucía, Heward, James, Wang, Qiaoying, Karim, Saadia A., Boughetane, Lina, Milton, Christopher, Uyulur, Firat, Morton, Jennifer P., Kocher, Hemant M., Grose, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918430/
https://www.ncbi.nlm.nih.gov/pubmed/36357571
http://dx.doi.org/10.1038/s41388-022-02513-5

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