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Implementation of computationally efficient numerical approach to analyze a Covid-19 pandemic model

Corona virus disease (Covid-19) which has caused frustration in the human community remains the concern of the globe as every government struggles to defeat the pandemic. To deal with the situation, we have extensively studied a deadly Covid-19 model to provide a deep insight into the disease dynami...

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Autores principales: Butt, Azhar Iqbal Kashif, Rafiq, Muhammad, Ahmad, Waheed, Ahmad, Naeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918432/
http://dx.doi.org/10.1016/j.aej.2023.01.052
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author Butt, Azhar Iqbal Kashif
Rafiq, Muhammad
Ahmad, Waheed
Ahmad, Naeed
author_facet Butt, Azhar Iqbal Kashif
Rafiq, Muhammad
Ahmad, Waheed
Ahmad, Naeed
author_sort Butt, Azhar Iqbal Kashif
collection PubMed
description Corona virus disease (Covid-19) which has caused frustration in the human community remains the concern of the globe as every government struggles to defeat the pandemic. To deal with the situation, we have extensively studied a deadly Covid-19 model to provide a deep insight into the disease dynamics. A mathematical analysis of the model utilizing preventive measures is performed with the aim to reduce the disease burden. Some comprehensive mathematical techniques are employed to demonstrate several essential properties of solutions. To start with, we proved the existence and uniqueness of solutions. Equilibrium points are stated both in the absence and presence of the pandemic. Biologically important quantity known as threshold parameter is computed to handle the future disease dynamics and analyzed for its sensitivity. We proved the stability of the proposed model at equilibrium points by employing necessary conditions on threshold parameter. A reliable and competitive numerical analysis is conducted to observe the effectiveness of implemented strategies and to verify obtained analytical results. The most sensitive parameters are determined through sensitivity analysis. An important feature of this study is to employ Non-Standard Finite Difference (NSFD) numerical scheme to solve the system instead of other standard methods like Runge–Kutta method of order 4 (RK4). Finally, several numerical simulations are performed to validate our former theoretical analysis. Numerical results exhibiting dynamical behavior of Covid-19 system under the influence of involved parameters suggest that both the implemented strategies, especially quarantine of exposed individuals, are effective for the substantial reduction in the diseased population and to achieve the herd immunity.
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spelling pubmed-99184322023-02-13 Implementation of computationally efficient numerical approach to analyze a Covid-19 pandemic model Butt, Azhar Iqbal Kashif Rafiq, Muhammad Ahmad, Waheed Ahmad, Naeed Alexandria Engineering Journal Original Article Corona virus disease (Covid-19) which has caused frustration in the human community remains the concern of the globe as every government struggles to defeat the pandemic. To deal with the situation, we have extensively studied a deadly Covid-19 model to provide a deep insight into the disease dynamics. A mathematical analysis of the model utilizing preventive measures is performed with the aim to reduce the disease burden. Some comprehensive mathematical techniques are employed to demonstrate several essential properties of solutions. To start with, we proved the existence and uniqueness of solutions. Equilibrium points are stated both in the absence and presence of the pandemic. Biologically important quantity known as threshold parameter is computed to handle the future disease dynamics and analyzed for its sensitivity. We proved the stability of the proposed model at equilibrium points by employing necessary conditions on threshold parameter. A reliable and competitive numerical analysis is conducted to observe the effectiveness of implemented strategies and to verify obtained analytical results. The most sensitive parameters are determined through sensitivity analysis. An important feature of this study is to employ Non-Standard Finite Difference (NSFD) numerical scheme to solve the system instead of other standard methods like Runge–Kutta method of order 4 (RK4). Finally, several numerical simulations are performed to validate our former theoretical analysis. Numerical results exhibiting dynamical behavior of Covid-19 system under the influence of involved parameters suggest that both the implemented strategies, especially quarantine of exposed individuals, are effective for the substantial reduction in the diseased population and to achieve the herd immunity. THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. 2023-04-15 2023-02-03 /pmc/articles/PMC9918432/ http://dx.doi.org/10.1016/j.aej.2023.01.052 Text en © 2023 THE AUTHORS Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Article
Butt, Azhar Iqbal Kashif
Rafiq, Muhammad
Ahmad, Waheed
Ahmad, Naeed
Implementation of computationally efficient numerical approach to analyze a Covid-19 pandemic model
title Implementation of computationally efficient numerical approach to analyze a Covid-19 pandemic model
title_full Implementation of computationally efficient numerical approach to analyze a Covid-19 pandemic model
title_fullStr Implementation of computationally efficient numerical approach to analyze a Covid-19 pandemic model
title_full_unstemmed Implementation of computationally efficient numerical approach to analyze a Covid-19 pandemic model
title_short Implementation of computationally efficient numerical approach to analyze a Covid-19 pandemic model
title_sort implementation of computationally efficient numerical approach to analyze a covid-19 pandemic model
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918432/
http://dx.doi.org/10.1016/j.aej.2023.01.052
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