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Genome-scale model of Pseudomonas aeruginosa metabolism unveils virulence and drug potentiation

Pseudomonas aeruginosa is one of the leading causes of hospital-acquired infections. To decipher the metabolic mechanisms associated with virulence and antibiotic resistance, we have developed an updated genome-scale model (GEM) of P. aeruginosa. The model (iSD1509) is an extensively curated, three-...

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Detalles Bibliográficos
Autores principales: Dahal, Sanjeev, Renz, Alina, Dräger, Andreas, Yang, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918512/
https://www.ncbi.nlm.nih.gov/pubmed/36765199
http://dx.doi.org/10.1038/s42003-023-04540-8