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Bile salt hydrolase in non-enterotoxigenic Bacteroides potentiates colorectal cancer

Bile salt hydrolase (BSH) in Bacteroides is considered a potential drug target for obesity-related metabolic diseases, but its involvement in colon tumorigenesis has not been explored. BSH-expressing Bacteroides is found at high abundance in the stools of colorectal cancer (CRC) patients  with overw...

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Detalles Bibliográficos
Autores principales: Sun, Lulu, Zhang, Yi, Cai, Jie, Rimal, Bipin, Rocha, Edson R., Coleman, James P., Zhang, Chenran, Nichols, Robert G., Luo, Yuhong, Kim, Bora, Chen, Yaozong, Krausz, Kristopher W., Harris, Curtis C., Patterson, Andrew D., Zhang, Zhipeng, Takahashi, Shogo, Gonzalez, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918522/
https://www.ncbi.nlm.nih.gov/pubmed/36765047
http://dx.doi.org/10.1038/s41467-023-36089-9