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Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer

Despite insights gained by bulk DNA sequencing of cancer it remains challenging to resolve the admixture of normal and tumor cells, and/or of distinct tumor subclones; high-throughput single-cell DNA sequencing circumvents these and brings cancer genomic studies to higher resolution. However, its ap...

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Detalles Bibliográficos
Autores principales: Zhang, Haochen, Karnoub, Elias-Ramzey, Umeda, Shigeaki, Chaligné, Ronan, Masilionis, Ignas, McIntyre, Caitlin A., Sashittal, Palash, Hayashi, Akimasa, Zucker, Amanda, Mullen, Katelyn, Hong, Jungeui, Makohon-Moore, Alvin, Iacobuzio-Donahue, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918733/
https://www.ncbi.nlm.nih.gov/pubmed/36765116
http://dx.doi.org/10.1038/s41467-023-36344-z