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Long-term platinum-based drug accumulation in cancer-associated fibroblasts promotes colorectal cancer progression and resistance to therapy
A substantial proportion of cancer patients do not benefit from platinum-based chemotherapy (CT) due to the emergence of drug resistance. Here, we apply elemental imaging to the mapping of CT biodistribution after therapy in residual colorectal cancer and achieve a comprehensive analysis of the gene...
Autores principales: | Linares, Jenniffer, Sallent-Aragay, Anna, Badia-Ramentol, Jordi, Recort-Bascuas, Alba, Méndez, Ana, Manero-Rupérez, Noemí, Re, Daniele Lo, Rivas, Elisa I., Guiu, Marc, Zwick, Melissa, Iglesias, Mar, Martinez-Ciarpaglini, Carolina, Tarazona, Noelia, Varese, Monica, Hernando-Momblona, Xavier, Cañellas-Socias, Adrià, Orrillo, Mayra, Garrido, Marta, Saoudi, Nadia, Elez, Elena, Navarro, Pilar, Tabernero, Josep, Gomis, Roger R., Batlle, Eduard, Pisonero, Jorge, Cervantes, Andres, Montagut, Clara, Calon, Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918738/ https://www.ncbi.nlm.nih.gov/pubmed/36765091 http://dx.doi.org/10.1038/s41467-023-36334-1 |
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