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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
BACKGROUND: Cancer immunity is based on the interaction of a multitude of cells in the spatial context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated to fundamentally improve the accuracy in predicting disease progression. METHODS: Through a multiplex in situ a...
Autores principales: | Mezheyeuski, Artur, Backman, Max, Mattsson, Johanna, Martín-Bernabé, Alfonso, Larsson, Chatarina, Hrynchyk, Ina, Hammarström, Klara, Ström, Simon, Ekström, Joakim, Mauchanski, Siarhei, Khelashvili, Salome, Lindberg, Amanda, Agnarsdóttir, Margrét, Edqvist, Per-Henrik, Huvila, Jutta, Segersten, Ulrika, Malmström, Per-Uno, Botling, Johan, Nodin, Björn, Hedner, Charlotta, Borg, David, Brändstedt, Jenny, Sartor, Hanna, Leandersson, Karin, Glimelius, Bengt, Portyanko, Anna, Ponten, Fredrik, Jirström, Karin, Micke, Patrick, Sjöblom, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918750/ https://www.ncbi.nlm.nih.gov/pubmed/36724681 http://dx.doi.org/10.1016/j.ebiom.2023.104452 |
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