ACT001 Relieves NMOSD Symptoms by Reducing Astrocyte Damage with an Autoimmune Antibody

Neuromyelitis optica spectrum disorder (NMOSD) is a central nervous system inflammatory demyelinating disease, the pathogenesis of which involves autoantibodies targeting the extracellular epitopes of aquaporin-4 on astrocytes. We neutralized the AQP4-IgG from NMOSD patient sera using synthesized AQ...

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Detalles Bibliográficos
Autores principales: Li, Hongen, Yang, Mo, Song, Honglu, Sun, Mingming, Zhou, Huanfen, Fu, Junxia, Zhou, Di, Bai, Wenhao, Chen, Biyue, Lai, Mengying, Kang, Hao, Wei, Shihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918908/
https://www.ncbi.nlm.nih.gov/pubmed/36771078
http://dx.doi.org/10.3390/molecules28031412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918908/
https://www.ncbi.nlm.nih.gov/pubmed/36771078
http://dx.doi.org/10.3390/molecules28031412

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