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ACT001 Relieves NMOSD Symptoms by Reducing Astrocyte Damage with an Autoimmune Antibody

Neuromyelitis optica spectrum disorder (NMOSD) is a central nervous system inflammatory demyelinating disease, the pathogenesis of which involves autoantibodies targeting the extracellular epitopes of aquaporin-4 on astrocytes. We neutralized the AQP4-IgG from NMOSD patient sera using synthesized AQ...

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Detalles Bibliográficos
Autores principales:	Li, Hongen, Yang, Mo, Song, Honglu, Sun, Mingming, Zhou, Huanfen, Fu, Junxia, Zhou, Di, Bai, Wenhao, Chen, Biyue, Lai, Mengying, Kang, Hao, Wei, Shihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918908/ https://www.ncbi.nlm.nih.gov/pubmed/36771078 http://dx.doi.org/10.3390/molecules28031412

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