Cargando…
Amyloid-like RIP1/RIP3 RHIM Fragments’ Characterization and Application as a Drug Depot
Amyloid aggregates play a major role in diseases as well as in normal physiological function. Receptor-interacting protein kinases 1 and 3 (RIP1/RIP3) aggregates complexes in cellular necroptosis is one example of protein aggregation in normal cellular function. Although recently there have been sev...
Autores principales: | Ismail, Maytham, Kanapathipillai, Mathumai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918910/ https://www.ncbi.nlm.nih.gov/pubmed/36771145 http://dx.doi.org/10.3390/molecules28031480 |
Ejemplares similares
-
A Novel Class of RIP1/RIP3 Dual Inhibitors
por: Zhou, Ting, et al.
Publicado: (2020) -
Life after death: RIP1 and RIP3 move beyond necroptosis
por: Berger, SB, et al.
Publicado: (2016) -
The RIP1–RIP3 Complex Mediates Osteocyte Necroptosis after Ovariectomy in Rats
por: Cui, Hongwang, et al.
Publicado: (2016) -
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
por: Zhang, Yingying, et al.
Publicado: (2017) -
RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3
por: Lukens, John R., et al.
Publicado: (2013)