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Utilizing the Off-Target Effects of T1R3 Antagonist Lactisole to Enhance Nitric Oxide Production in Basal Airway Epithelial Cells

Human airway sweet (T1R2 + T1R3), umami (T1R1 + T1R3), and bitter taste receptors (T2Rs) are critical components of the innate immune system, acting as sensors to monitor pathogenic growth. T2Rs detect bacterial products or bitter compounds to drive nitric oxide (NO) production in both healthy and d...

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Detalles Bibliográficos
Autores principales:	McMahon, Derek B., Jolivert, Jennifer F., Kuek, Li Eon, Adappa, Nithin D., Palmer, James N., Lee, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919013/ https://www.ncbi.nlm.nih.gov/pubmed/36771227 http://dx.doi.org/10.3390/nu15030517

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