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An Electrochemical Sensor for Sulfadiazine Determination Based on a Copper Nanoparticles/Molecularly Imprinted Overoxidized Polypyrrole Composite
To protect consumers from risks related to overexposure to sulfadiazine, total residues of this antibacterial agent in animal-origin foodstuffs not exceed international regulations. To this end, a new electrochemical sensor based on a molecularly imprinted polymer nanocomposite using overoxidized po...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919664/ https://www.ncbi.nlm.nih.gov/pubmed/36772311 http://dx.doi.org/10.3390/s23031270 |
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author | Elamin, Manahil Babiker Ali, Shazalia Mahmoud Ahmed Essousi, Houda Chrouda, Amani Alhaidari, Laila M. Jaffrezic-Renault, Nicole Barhoumi, Houcine |
author_facet | Elamin, Manahil Babiker Ali, Shazalia Mahmoud Ahmed Essousi, Houda Chrouda, Amani Alhaidari, Laila M. Jaffrezic-Renault, Nicole Barhoumi, Houcine |
author_sort | Elamin, Manahil Babiker |
collection | PubMed |
description | To protect consumers from risks related to overexposure to sulfadiazine, total residues of this antibacterial agent in animal-origin foodstuffs not exceed international regulations. To this end, a new electrochemical sensor based on a molecularly imprinted polymer nanocomposite using overoxidized polypyrrole and copper nanoparticles for the detection of sulfadiazine is elaborated. After optimization of the preparation of the electrochemical sensors, their differential pulse voltammetric signal exhibits an excellent stability and reproducibility at 1.05 V, with a large linear range between 10(−9) and 10(−5) mol L(−1) and a low detection limit of 3.1 × 10(−10) mol L(−1). The produced sulfadiazine sensor was successfully tested in real milk samples. The combination of the properties of the electrical conduction of copper nanoparticles with the properties of the preconcentration of the molecularly imprinted overoxidized polypyrrole allows for the highly sensitive detection of sulfadiazine, even in real milk samples. This strategy is new and leads to the lowest detection limit yet achieved, compared to those of the previously published sulfadiazine electrochemical sensors. |
format | Online Article Text |
id | pubmed-9919664 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99196642023-02-12 An Electrochemical Sensor for Sulfadiazine Determination Based on a Copper Nanoparticles/Molecularly Imprinted Overoxidized Polypyrrole Composite Elamin, Manahil Babiker Ali, Shazalia Mahmoud Ahmed Essousi, Houda Chrouda, Amani Alhaidari, Laila M. Jaffrezic-Renault, Nicole Barhoumi, Houcine Sensors (Basel) Article To protect consumers from risks related to overexposure to sulfadiazine, total residues of this antibacterial agent in animal-origin foodstuffs not exceed international regulations. To this end, a new electrochemical sensor based on a molecularly imprinted polymer nanocomposite using overoxidized polypyrrole and copper nanoparticles for the detection of sulfadiazine is elaborated. After optimization of the preparation of the electrochemical sensors, their differential pulse voltammetric signal exhibits an excellent stability and reproducibility at 1.05 V, with a large linear range between 10(−9) and 10(−5) mol L(−1) and a low detection limit of 3.1 × 10(−10) mol L(−1). The produced sulfadiazine sensor was successfully tested in real milk samples. The combination of the properties of the electrical conduction of copper nanoparticles with the properties of the preconcentration of the molecularly imprinted overoxidized polypyrrole allows for the highly sensitive detection of sulfadiazine, even in real milk samples. This strategy is new and leads to the lowest detection limit yet achieved, compared to those of the previously published sulfadiazine electrochemical sensors. MDPI 2023-01-22 /pmc/articles/PMC9919664/ /pubmed/36772311 http://dx.doi.org/10.3390/s23031270 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Elamin, Manahil Babiker Ali, Shazalia Mahmoud Ahmed Essousi, Houda Chrouda, Amani Alhaidari, Laila M. Jaffrezic-Renault, Nicole Barhoumi, Houcine An Electrochemical Sensor for Sulfadiazine Determination Based on a Copper Nanoparticles/Molecularly Imprinted Overoxidized Polypyrrole Composite |
title | An Electrochemical Sensor for Sulfadiazine Determination Based on a Copper Nanoparticles/Molecularly Imprinted Overoxidized Polypyrrole Composite |
title_full | An Electrochemical Sensor for Sulfadiazine Determination Based on a Copper Nanoparticles/Molecularly Imprinted Overoxidized Polypyrrole Composite |
title_fullStr | An Electrochemical Sensor for Sulfadiazine Determination Based on a Copper Nanoparticles/Molecularly Imprinted Overoxidized Polypyrrole Composite |
title_full_unstemmed | An Electrochemical Sensor for Sulfadiazine Determination Based on a Copper Nanoparticles/Molecularly Imprinted Overoxidized Polypyrrole Composite |
title_short | An Electrochemical Sensor for Sulfadiazine Determination Based on a Copper Nanoparticles/Molecularly Imprinted Overoxidized Polypyrrole Composite |
title_sort | electrochemical sensor for sulfadiazine determination based on a copper nanoparticles/molecularly imprinted overoxidized polypyrrole composite |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919664/ https://www.ncbi.nlm.nih.gov/pubmed/36772311 http://dx.doi.org/10.3390/s23031270 |
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