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The NLRP3 Inflammasome Is Required for Protection Against Pseudomonas Keratitis

PURPOSE: The current study was designed to examine the role of the NLRP3 inflammasome pathway in the clearance of Pseudomonas aeruginosa (PA) infection in mouse corneas. METHODS: Corneas of wild type and NLRP3(−/−) mice were infected with PA. The severity of bacterial keratitis was graded on days 1...

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Detalles Bibliográficos
Autores principales:	Ramadan, Abdulraouf, Cao, Zhiyi, Gadjeva, Mihaela, Zaidi, Tanweer S., Rathinam, Vijay A., Panjwani, Noorjahan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Immunology and Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919680/ https://www.ncbi.nlm.nih.gov/pubmed/36749596 http://dx.doi.org/10.1167/iovs.64.2.11

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