Establishment of LC-MS/MS Method for Determination of GMDTC in Rat Plasma and Its Application in Preclinical Pharmacokinetics

Sodium (S)-2-(dithiocarboxylato((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)amino)-4(methylthio)butanoate (GMDTC) is the first compound to use cadmium repellent as an indication. In this paper, we established and validated a bioanalytical method for the determination of GMDTC in rat plasma, and used i...

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Detalles Bibliográficos
Autores principales: Hu, Wei, Zhong, Zhi-Yong, Gao, Yu-Ting, Ren, Xue-Feng, Liu, Hai-Yang, Tang, Xiao-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919763/
https://www.ncbi.nlm.nih.gov/pubmed/36770860
http://dx.doi.org/10.3390/molecules28031191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919763/
https://www.ncbi.nlm.nih.gov/pubmed/36770860
http://dx.doi.org/10.3390/molecules28031191

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