Cargando…

Establishment of LC-MS/MS Method for Determination of GMDTC in Rat Plasma and Its Application in Preclinical Pharmacokinetics

Sodium (S)-2-(dithiocarboxylato((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)amino)-4(methylthio)butanoate (GMDTC) is the first compound to use cadmium repellent as an indication. In this paper, we established and validated a bioanalytical method for the determination of GMDTC in rat plasma, and used i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Wei, Zhong, Zhi-Yong, Gao, Yu-Ting, Ren, Xue-Feng, Liu, Hai-Yang, Tang, Xiao-Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919763/ https://www.ncbi.nlm.nih.gov/pubmed/36770860 http://dx.doi.org/10.3390/molecules28031191

Ejemplares similares

Largazole Pharmacokinetics in Rats by LC-MS/MS
por: Yu, Mingming, et al.
Publicado: (2014)

Determination of dihydromyricetin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study
por: Liu, Lu, et al.
Publicado: (2016)

Determination of cepharanthine in rat plasma by LC–MS/MS and its application to a pharmacokinetic study
por: Deng, Yingbin, et al.
Publicado: (2017)

Determination and pharmacokinetics study of UK-5099 in mouse plasma by LC–MS/MS
por: Zeng, Qingyuan, et al.
Publicado: (2022)

Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application
por: Liu, Yanping, et al.
Publicado: (2013)

Validated LC-MS/MS Method for the Determination of Scopoletin in Rat Plasma and Its Application to Pharmacokinetic Studies
por: Zeng, Yingchun, et al.
Publicado: (2015)

The LC-MS/MS-Based Measurement of Isopimaric Acid in Rat Plasma and Application of Pharmacokinetics
por: Huang, Doudou, et al.
Publicado: (2021)

Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats
por: Chen, Juan, et al.
Publicado: (2022)

LC–MS/MS determination and pharmacokinetic study of columbianadin in rat plasma after intravenous administration of pure columbianadin
por: Chang, Yan-xu, et al.
Publicado: (2014)

Determination of Epimedin B in Rat Plasma and Tissue by LC-MS/MS: Application in Pharmacokinetic and Tissue Distribution Studies
por: Feng, Qianru, et al.
Publicado: (2017)

Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS
por: Xu, Dan, et al.
Publicado: (2020)

Simultaneous Determination of Atorvastatin and Aspirin in Human Plasma by LC–MS/MS: Its Pharmacokinetic Application
por: Gajula, Ramakrishna, et al.
Publicado: (2012)

A validated LC–MS/MS method for the determination of tolterodine and its metabolite in rat plasma and application to pharmacokinetic study
por: Shaik, Rihana Parveen, et al.
Publicado: (2013)

Determination and pharmacokinetics study of oxyclozanide suspension in cattle by LC-MS/MS
por: Zhang, Jili, et al.
Publicado: (2019)

Precolumn derivatization LC–MS/MS method for the determination and pharmacokinetic study of glucosamine in human plasma and urine
por: Song, Min, et al.
Publicado: (2012)

Effects of triptolide on pharmacokinetics of amlodipine in rats by using LC–MS/MS
por: Zhang, Chengyin, et al.
Publicado: (2018)

Determination of Leuprolide–Fatty Acid Conjugate in Rat Plasma Using LC-MS/MS and Its Pharmacokinetics after Subcutaneous Administration in Rats
por: Seong, Gi-Sang, et al.
Publicado: (2022)

LC-MS/MS Determination and Pharmacokinetic Study of Pedunculoside in Rat Plasma after Oral Administration of Pedunculoside and Ilex rotunda Extract
por: Zhao, Waiou, et al.
Publicado: (2015)

LC-MS/MS Determination and Pharmacokinetic Study of Dehydrocorydaline in Rat Plasma after Oral Administration of Dehydrocorydaline and Corydalis yanhusuo Extract
por: Li, Qiu-Yue, et al.
Publicado: (2014)

Simultaneous Determination of Bufalin and Its Nine Metabolites in Rat Plasma for Characterization of Metabolic Profiles and Pharmacokinetic Study by LC–MS/MS
por: Wei, Wenlong, et al.
Publicado: (2019)

Development and Optimization of a High Sensitivity LC-MS/MS Method for the Determination of Hesperidin and Naringenin in Rat Plasma: Pharmacokinetic Approach
por: Araujo-León, Jesús Alfredo, et al.
Publicado: (2020)

Simultaneous Quantification of Baricitinib and Methotrexate in Rat Plasma by LC-MS/MS: Application to a Pharmacokinetic Study
por: Veeraraghavan, Sridhar, et al.
Publicado: (2016)

Development of an LC–MS/MS method for the quantitation of deoxyglycychloxazol in rat plasma and its application in pharmacokinetic study()
por: Li, Rongshan, et al.
Publicado: (2016)

Validated method to measure yakuchinone A in plasma by LC-MS/MS and its application to a pharmacokinetic study in rats
por: Chen, Feng, et al.
Publicado: (2014)

Rapid Determination of Isomeric Benzoylpaeoniflorin and Benzoylalbiflorin in Rat Plasma by LC-MS/MS Method
por: Zhou, Chuanqi, et al.
Publicado: (2017)

Simultaneous Determination of RDX and HMX in Rat Plasma by LC-MS/MS and its Applications
por: Zhang, Xi, et al.
Publicado: (2022)

Simultaneous determination of amlodipine, valsartan and hydrochlorothiazide by LC–ESI-MS/MS and its application to pharmacokinetics in rats
por: Gadepalli, Shankar Ganesh, et al.
Publicado: (2014)

Simultaneous determination of acetaminophen and oxycodone in human plasma by LC–MS/MS and its application to a pharmacokinetic study
por: Lu, Wei, et al.
Publicado: (2018)

UHPLC-MS/MS Determination, Pharmacokinetic, and Bioavailability Study of Taxifolin in Rat Plasma after Oral Administration of its Nanodispersion
por: Yang, Chun-Juan, et al.
Publicado: (2016)

Simultaneous Determination of Columbianadin and Its Metabolite Columbianetin in Rat Plasma by LC-MS/MS: Application to Pharmacokinetics of Columbianadin after Oral Administration
por: Li, Jin, et al.
Publicado: (2018)

An LC-MS/MS Method for Simultaneous Determination of the Toxic and Active Components of Cortex Periplocae in Rat Plasma and Application to a Pharmacokinetic Study
por: Li, Zhen, et al.
Publicado: (2019)

Determination of the Peptide AWRK6 in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) and Its Application to Pharmacokinetics
por: Jin, Lili, et al.
Publicado: (2021)

A rapid LC-MS/MS method for simultaneous determination of quetiapine and duloxetine in rat plasma and its application to pharmacokinetic interaction study
por: Chen, Xiujuan, et al.
Publicado: (2018)

Quantification of tolvaptan in rabbit plasma by LC–MS/MS: Application to a pharmacokinetic study()
por: Moola, Kumar S., et al.
Publicado: (2015)

LC–MS/MS method for the quantitation of decitabine and venetoclax in rat plasma after SPE: Application to pharmacokinetic study
por: Alnasser, Abdulaziz I., et al.
Publicado: (2023)

Preclinical Pharmacokinetics of Scoparone, Geniposide and Rhein in an Herbal Medicine Using a Validated LC-MS/MS Method
por: Hsueh, Tun-Pin, et al.
Publicado: (2018)

LC-MS/MS Method for Determination of Hydroxychloroquine and Metabolites: Application in a Pharmacokinetic Study
por: Cui, Lili, et al.
Publicado: (2022)

Simultaneous determination of telmisartan and amlodipine in human plasma by LC–MS/MS and its application in a human pharmacokinetic study
por: Ravi, Vasu Babu, et al.
Publicado: (2012)

Simultaneous determination of pioglitazone and candesartan in human plasma by LC-MS/MS and its application to a human pharmacokinetic study
por: Kumari Karra, Vijaya, et al.
Publicado: (2012)

LC–MS/MS assay for the determination of natamycin in rabbit and human plasma: Application to a pharmacokinetics and protein binding study
por: Chhonker, Yashpal Singh, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_767vt7e5ivkkc7fu2duhu8gd9b