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Cyclic Glycine-Proline (cGP) Normalises Insulin-Like Growth Factor-1 (IGF-1) Function: Clinical Significance in the Ageing Brain and in Age-Related Neurological Conditions

Insulin-like growth factor-1 (IGF-1) function declines with age and is associated with brain ageing and the progression of age-related neurological conditions. The reversible binding of IGF-1 to IGF binding protein (IGFBP)-3 regulates the amount of bioavailable, functional IGF-1 in circulation. Cycl...

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Detalles Bibliográficos
Autores principales: Guan, Jian, Li, Fengxia, Kang, Dali, Anderson, Tim, Pitcher, Toni, Dalrymple-Alford, John, Shorten, Paul, Singh-Mallah, Gagandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919809/
https://www.ncbi.nlm.nih.gov/pubmed/36770687
http://dx.doi.org/10.3390/molecules28031021